Literature DB >> 13163330

Cellular mechanisms of protein metabolism in the nephron. II. The histochemical characteristics of protein absorption droplets.

J OLIVER, M J MOSES, M C MACDOWELL, Y C LEE.   

Abstract

Histochemical methods show not only the presence of absorbed protein in the cellular droplet, but also the general identity of its constituent substances with those of the mitochondrial rodlets. Both contain considerable amounts of phospholipid and probably some PNA. The reactivity of the cytoplasmic constituents in droplet and in rodlet are different, however, since in the droplet these substances stain more intensely. As judged by variations observed in this intensity during the evolution of the droplet, these constituents and the absorbed protein vary in their proportions and amount. The droplet would appear to be a highly active center of protein metabolism.

Entities:  

Keywords:  KIDNEYS/metabolism; PROTEINS/metabolism

Mesh:

Substances:

Year:  1954        PMID: 13163330      PMCID: PMC2136349          DOI: 10.1084/jem.99.6.605

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  4 in total

1.  The structure of the metabolic process in the nephron.

Authors:  J OLIVER
Journal:  J Mt Sinai Hosp N Y       Date:  1948 Nov-Dec

2.  The Gram stain.

Authors:  J W BARTHOLOMEW; T MITTWER
Journal:  Bacteriol Rev       Date:  1952-03

3.  The problem of a standardized technic for the methyl-green-pyronin stain.

Authors:  E B TAFT
Journal:  Stain Technol       Date:  1951-07

4.  Cellular mechanisms of protein metabolism in the nephron. I. The structural aspects of proteinuria; tubular absorption, droplet formation, and the disposal of proteins.

Authors:  J OLIVER; M MACDOWELL; Y C LEE
Journal:  J Exp Med       Date:  1954-06-01       Impact factor: 14.307

  4 in total
  19 in total

1.  Observations on the histological effects of sub-lethal doses of cadmium chloride in the rabbit. II. The effect on the kidney cortex.

Authors:  C L FOSTER; E CAMERON
Journal:  J Anat       Date:  1963-04       Impact factor: 2.610

2.  [On the transformation of chondriome by accumulation of macromolecular substances (dextran, periston). Electron microscopic investigations on the reticuloendothelium of the rat spleen].

Authors:  G GABLER
Journal:  Virchows Arch Pathol Anat Physiol Klin Med       Date:  1960

3.  A comparative cytochemical and cytologic study of vitamin D induced nephrocalcinosis.

Authors:  D G SCARPELLI; G TREMBLAY; A G PEARSE
Journal:  Am J Pathol       Date:  1960-03       Impact factor: 4.307

4.  Histologic and histochemical studies of the rabbit glomerulonephritis produced by specific antikidney duck serum.

Authors:  M WACHSTEIN; K LANGE
Journal:  Am J Pathol       Date:  1958 Sep-Oct       Impact factor: 4.307

5.  The metabolism of fluorescein-labelled and unlabelled egg-white in the renal tubules of the mouse.

Authors:  H MAYERSBACH; A G PEARSE
Journal:  Br J Exp Pathol       Date:  1956-02

6.  Naturally occurring protein droplets in the proximal tubule of the rat's kidney.

Authors:  J LOGOTHETOPOULOS; K WEINBREN
Journal:  Br J Exp Pathol       Date:  1955-08

7.  A THEORY CONCERNING THE MECHANISM OF ALLERGIC DISEASES.

Authors:  R W Lippman
Journal:  Proc Natl Acad Sci U S A       Date:  1955-06-15       Impact factor: 11.205

8.  Cellular mechanisms of protein metabolism in the nephron. V. The intracellular partition and the incorporation into protein of intravenously injected L-lysine.

Authors:  N KRETCHMER; F J CHEROT
Journal:  J Exp Med       Date:  1954-06-01       Impact factor: 14.307

9.  THE EFFECT OF POTASSIUM DEFICIENCY ON THE REABSORPTION OF PROTEIN IN THE RENAL TUBULE OF THE RAT.

Authors:  A B MORRISON; K D GARDNER
Journal:  J Exp Med       Date:  1963-10-01       Impact factor: 14.307

10.  EXPERIMENTAL STUDIES IN ACUTE RENAL FAILURE. II. FINE STRUCTURE CHANGES IN TUBULES ASSOCIATED WITH RENAL FAILURE INDUCED BY GLOBIN.

Authors:  M G MENEFEE; C B MUELLER; T B MILLER; J K MYERS; A L BELL
Journal:  J Exp Med       Date:  1964-12-01       Impact factor: 14.307

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