Literature DB >> 13163324

Myocardial necrosis produced in animals by means of crystalline streptococcal proteinase.

A KELLNER, T ROBERTSON.   

Abstract

Focal myocardial necrosis that was often extensive was found in a high percentage of rabbits, guinea pigs, and mice given a single intravenous injection of crystalline streptococcal proteinase. The findings are discussed in relation to their possible implications for the pathogenesis of the cardiac lesions of rheumatic fever.

Entities:  

Keywords:  MYOCARDIUM/diseases; NECROSIS/experimental; PROTEASES

Mesh:

Substances:

Year:  1954        PMID: 13163324      PMCID: PMC2136258          DOI: 10.1084/jem.99.5.495

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  6 in total

1.  The etiology of rheumatic fever.

Authors:  H P SWIFT
Journal:  Ann Intern Med       Date:  1949-11       Impact factor: 25.391

2.  Selective necrosis of cardiac and skeletal muscle induced experimentally by means of proteolytic enzyme solutions given intravenously.

Authors:  A KELLNER; T ROBERTSON
Journal:  J Exp Med       Date:  1954-04-01       Impact factor: 14.307

3.  A STUDY OF THE INHIBITION OF STREPTOCOCCAL PROTEINASE BY SERA OF NORMAL AND IMMUNE ANIMALS AND OF PATIENTS INFECTED WITH GROUP A HEMOLYTIC STREPTOCOCCI.

Authors:  E W Todd
Journal:  J Exp Med       Date:  1947-05-31       Impact factor: 14.307

4.  THE CARDIOTOXIC ACTION OF PREPARATIONS CONTAINING THE OXYGEN-LABILE HEMOLYSIN OF STREPTOCOCCUS PYOGENES : I. INCREASED SENSITIVITY OF THE ISOLATED FROG'S HEART TO REPEATED APPLICATION OF THE TOXIN.

Authors:  A W Bernheimer; G L Cantoni
Journal:  J Exp Med       Date:  1945-03-01       Impact factor: 14.307

5.  The inactivation of complement and its components by plasmin.

Authors:  L PILLEMER; O D RATNOFF; L BLUM; I H LEPOW
Journal:  J Exp Med       Date:  1953-04       Impact factor: 14.307

6.  A PROTEOLYTIC ENZYME PRODUCED BY GROUP A STREPTOCOCCI WITH SPECIAL REFERENCE TO ITS EFFECT ON THE TYPE-SPECIFIC M ANTIGEN.

Authors:  S D Elliott
Journal:  J Exp Med       Date:  1945-06-01       Impact factor: 14.307

  6 in total
  15 in total

1.  [Serologic group determination of Streptococci by means of fermentative antigen preparation].

Authors:  K KLINGE
Journal:  Z Hyg Infektionskr       Date:  1956

2.  Organ Lesions Produced in Rabbits by Group a Streptococci and Some of their Extracellular Products.

Authors:  N Zeiri; Z Bentwich; J H Boss; I Ginsburg; T N Harris
Journal:  Am J Pathol       Date:  1967-09       Impact factor: 4.307

3.  Substitution of cysteine 192 in a highly conserved Streptococcus pyogenes extracellular cysteine protease (interleukin 1beta convertase) alters proteolytic activity and ablates zymogen processing.

Authors:  J M Musser; K Stockbauer; V Kapur; G W Rudgers
Journal:  Infect Immun       Date:  1996-06       Impact factor: 3.441

4.  Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: an integrin-binding cysteine protease.

Authors:  T F Kagawa; J C Cooney; H M Baker; S McSweeney; M Liu; S Gubba; J M Musser; E N Baker
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-29       Impact factor: 11.205

5.  Absence of a cysteine protease effect on bacterial virulence in two murine models of human invasive group A streptococcal infection.

Authors:  C D Ashbaugh; M R Wessels
Journal:  Infect Immun       Date:  2001-11       Impact factor: 3.441

Review 6.  Streptococcal rheumatic carditis.

Authors:  S K Unny; B L Middlebrooks
Journal:  Microbiol Rev       Date:  1983-03

7.  Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains.

Authors:  S Lukomski; S Sreevatsan; C Amberg; W Reichardt; M Woischnik; A Podbielski; J M Musser
Journal:  J Clin Invest       Date:  1997-06-01       Impact factor: 14.808

8.  Effect of group A streptococcal cysteine protease on invasion of epithelial cells.

Authors:  P J Tsai; C F Kuo; K Y Lin; Y S Lin; H Y Lei; F F Chen; J R Wang; J J Wu
Journal:  Infect Immun       Date:  1998-04       Impact factor: 3.441

9.  Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.

Authors:  V Kapur; M W Majesky; L L Li; R A Black; J M Musser
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

10.  Role of proteinase in the formation of inhibitory levels of hematin by group A streptococcus cultures on blood-containing media.

Authors:  W L Hynes; J R Tagg
Journal:  J Clin Microbiol       Date:  1986-05       Impact factor: 5.948

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