Literature DB >> 1316091

Lipid peroxidation in human breast cancer cells in response to gamma-linolenic acid and iron.

S Takeda1, D F Horrobin, M Manku, P G Sim, G Ells, V Simmons.   

Abstract

Lipid peroxidation in human breast cancer (ZR-75-1) cells and cancer cell killing were confirmed by using ultraviolet (UV)-spectrophotometry and mass spectrometry (MS). ZR-75-1 cells and human normal fibroblast CCD-41-SK (41Sk) cells were cultured with gamma-linolenic acid (GLA) and ferrous iron Fe (II) combinations. Formation of lipid peroxide and cytotoxic effect were highest in ZR-75-1 cells treated with GLA + Fe (II), though 41Sk cells showed little evidence of either lipid peroxidation or cytotoxity. These results indicate a cancer-cell-specific lipid peroxidation mechanism in association with the selective cancer cell killing effect in response to GLA.

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Year:  1992        PMID： 1316091

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  8 in total

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Authors:  R A Canuto; M Ferro; R A Salvo; A M Bassi; A Trombetta; M Maggiora; G Martinasso; R Lindahl; G Muzio
Journal:  Biochem J       Date:  2001-08-01       Impact factor: 3.857

2.  Dose-dependent inhibition of cell proliferation induced by lipid peroxidation products in rat hepatoma cells after enrichment with arachidonic acid.

Authors:  G Muzio; R A Salvo; A Trombetta; R Autelli; M Maggiora; M Terreno; M U Dianzani; R A Canuto
Journal:  Lipids       Date:  1999-07       Impact factor: 1.880

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Authors:  V Chajès; W Sattler; A Stranzl; G M Kostner
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4.  The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells.

Authors:  W G Jiang; S Hiscox; R P Bryce; D F Horrobin; R E Mansel
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5.  Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation.

Authors:  Jérôme Roy; Liliam Teixeira Oliveira; Camille Oger; Jean-Marie Galano; Valerie Bultel-Poncé; Sylvain Richard; Andrea Grabe Guimaraes; José Mário Carneiro Vilela; Margareth Spangler Andrade; Thierry Durand; Pierre Besson; Vanessa Carla Furtado Mosqueira; Jean-Yves Le Guennec
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6.  Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid.

Authors:  W G Jiang; S Hiscox; M B Hallett; C Scott; D F Horrobin; M C Puntis
Journal:  Br J Cancer       Date:  1995-04       Impact factor: 7.640

7.  n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines.

Authors:  S I Grammatikos; P V Subbaiah; T A Victor; W M Miller
Journal:  Br J Cancer       Date:  1994-08       Impact factor: 7.640

8.  Possible Protective Effects of TA on the Cancerous Effect of Mesotrione.

Authors:  Agata Jabłońska-Trypuć; Urszula Wydro; Elżbieta Wołejko; Joanna Rodziewicz; Andrzej Butarewicz
Journal:  Nutrients       Date:  2020-05-08       Impact factor: 5.717
  8 in total

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