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Literature DB >> 1315923

The nerve growth factor receptor: a multicomponent system that mediates the actions of the neurotrophin family of proteins.

Abstract

Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin 3 (NT-3) are members of a family of structurally related proteins termed neurotrophins that promote the growth and survival of neurons in the central and peripheral nervous systems. Each of these proteins bind to at least two membrane receptors. One is the low affinity nerve growth factor receptor (p75), which binds each member of the neurotrophin family. The other is one of a family of tyrosine kinase receptors--trkA binds only NGF, the related trkB receptor binds BDNF and NT-3, and trkC binds NT-3 alone. This article reviews kinetic and biochemical information on p75 and its relationship to the trk gene products.

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Year: 1992 PMID： 1315923 DOI： 10.1007/bf02385000

Source DB: PubMed Journal: Mol Cell Biochem ISSN： 0300-8177 Impact factor: 3.396

161 in total

1. Disruption of cysteine-rich repeats of the p75 nerve growth factor receptor leads to loss of ligand binding.

Authors: H Yan; M V Chao
Journal: J Biol Chem Date: 1991-06-25 Impact factor: 5.157

Review 2. Keeping track of neurotrophin receptors.

Authors: M Bothwell
Journal: Cell Date: 1991-06-14 Impact factor: 41.582

3. Isolation and characterization of two novel rat ovarian lactogen receptor cDNA species.

Authors: R Zhang; E Buczko; C H Tsai-Morris; Z Z Hu; M L Dufau
Journal: Biochem Biophys Res Commun Date: 1990-04-30 Impact factor: 3.575

4. A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF.

Authors: S J Birren; D J Anderson
Journal: Neuron Date: 1990-02 Impact factor: 17.173

5. Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family.

Authors: A Hohn; J Leibrock; K Bailey; Y A Barde
Journal: Nature Date: 1990-03-22 Impact factor: 49.962

6. Inhibition of tyrosine kinase activity of the epidermal growth factor (EGF) receptor by a truncated receptor form that binds to EGF: role for interreceptor interaction in kinase regulation.

Authors: A Basu; M Raghunath; S Bishayee; M Das
Journal: Mol Cell Biol Date: 1989-02 Impact factor: 4.272

7. Nerve growth factor receptors on PC12 cells: evidence for two receptor classes with differing cytoskeletal association.

Authors: A L Schechter; M A Bothwell
Journal: Cell Date: 1981-06 Impact factor: 41.582

8. Developmental study of nerve growth factor receptor mRNA expression in the postnatal rat cerebellum.

Authors: A Wanaka; E M Johnson
Journal: Brain Res Dev Brain Res Date: 1990-09-01

9. Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor.

Authors: W C Fanslow; J E Sims; H Sassenfeld; P J Morrissey; S Gillis; S K Dower; M B Widmer
Journal: Science Date: 1990-05-11 Impact factor: 47.728

10. Neurotrophin-3: a neurotrophic factor related to NGF and BDNF.

Authors: P C Maisonpierre; L Belluscio; S Squinto; N Y Ip; M E Furth; R M Lindsay; G D Yancopoulos
Journal: Science Date: 1990-03-23 Impact factor: 47.728

17 in total

1. Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase family.

Authors: R M Katso; R B Russell; T S Ganesan
Journal: Mol Cell Biol Date: 1999-09 Impact factor: 4.272

Review 2. Specific protein markers for stem cell cross-talk with neighboring cells in the environment.

Authors: Kyung Soo Park; Seung Won Shin; Jeong-Woo Choi; Soong Ho Um
Journal: Int J Stem Cells Date: 2013-11 Impact factor: 2.500

3. Fates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradation.

Authors: Rafal Butowt; Christopher S von Bartheld
Journal: J Neurosci Date: 2009-08-26 Impact factor: 6.167

4. Sorting of internalized neurotrophins into an endocytic transcytosis pathway via the Golgi system: Ultrastructural analysis in retinal ganglion cells.

Authors: R Butowt; C S von Bartheld
Journal: J Neurosci Date: 2001-11-15 Impact factor: 6.167

5. Cholecystokinin-8 protects central cholinergic neurons against fimbria-fornix lesion through the up-regulation of nerve growth factor synthesis.

Authors: P Tirassa; L Aloe; C Stenfors; P Turrini; T Lundeberg
Journal: Proc Natl Acad Sci U S A Date: 1999-05-25 Impact factor: 11.205

6. Neurotrophin 3 rescues neuronal precursors from apoptosis and promotes neuronal differentiation in the embryonic metanephric kidney.

Authors: A Karavanov; K Sainio; J Palgi; M Saarma; L Saxen; H Sariola
Journal: Proc Natl Acad Sci U S A Date: 1995-11-21 Impact factor: 11.205

7. Chronic inflammation enhances NGF-β/TrkA system expression via EGFR/MEK/ERK pathway activation in Sjögren's syndrome.

Authors: Sabrina Lisi; Margherita Sisto; Domenico Ribatti; Massimo D'Amore; Raffella De Lucro; Maria Antonia Frassanito; Loredana Lorusso; Angelo Vacca; Dario Domenico Lofrumento
Journal: J Mol Med (Berl) Date: 2014-02-21 Impact factor: 4.599

8. The p75NTR signaling cascade mediates mechanical hyperalgesia induced by nerve growth factor injected into the rat hind paw.

Authors: A Khodorova; G D Nicol; G Strichartz
Journal: Neuroscience Date: 2013-10-01 Impact factor: 3.590

9. The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor.

Authors: Alla Khodorova; Grant D Nicol; Gary Strichartz
Journal: Neuroscience Date: 2016-11-05 Impact factor: 3.590

10. Modeled structure of the 75-kDa neurotrophin receptor.

Authors: B S Chapman; I D Kuntz
Journal: Protein Sci Date: 1995-09 Impact factor: 6.725