Literature DB >> 1315565

Infection of Chang cells with hepatitis C virus using hepatic biopsy specimens from patients with chronic hepatitis (type C).

T Ozeki1, K Hikiji, K Funakoshi, M Tsutsumi, A Yoshida.   

Abstract

The presence of hepatitis C virus sequence was detected in liver tissue extracts by the polymerase chain reaction (PCR) method using primers of non-coding region in six out of eight cases with chronic hepatitis seropositive for Chiron's antibody. Subsequently, liver extracts from these cases were added to cell cultures of Chang cells for 3 days. The liver extracts of the six cases positive for PCR appeared to infect the Chang cells.

Entities:  

Mesh：

Year:  1992        PMID： 1315565      PMCID： PMC2002462     

Source DB:  PubMed          Journal:  Int J Exp Pathol        ISSN： 0959-9673            Impact factor:   1.925


  4 in total

1.  Detection of hepatitis C virus genomes from patient's plasma using PCR method.

Authors:  N Enomoto; S Takase; A Takada; T Date
Journal:  Gastroenterol Jpn       Date:  1990-06

2.  Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis.

Authors:  H J Alter; R H Purcell; J W Shih; J C Melpolder; M Houghton; Q L Choo; G Kuo
Journal:  N Engl J Med       Date:  1989-11-30       Impact factor: 91.245

3.  Detection of hepatitis C viral sequences in blood donations by "nested" polymerase chain reaction and prediction of infectivity.

Authors:  J A Garson; R S Tedder; M Briggs; P Tuke; J A Glazebrook; A Trute; D Parker; J A Barbara; M Contreras; S Aloysius
Journal:  Lancet       Date:  1990-06-16       Impact factor: 79.321

4.  Infectivity of blood seropositive for hepatitis C virus antibodies.

Authors:  C L van der Poel; H W Reesink; W Schaasberg; A Leentvaar-Kuypers; E Bakker; P J Exel-Oehlers; P N Lelie
Journal:  Lancet       Date:  1990-03-10       Impact factor: 79.321
  4 in total

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