Literature DB >> 1315562

Sumatriptan and cerebral perfusion in healthy volunteers.

A K Scott1, S Grimes, K Ng, M Critchley, A M Breckenridge, C Thomson, A J Pilgrim.   

Abstract

1. The effect of sumatriptan on regional cerebral perfusion was studied in healthy volunteers. 2. Intravenous sumatriptan (2 mg) had no detectable effect on regional cerebral perfusion as measured using a SPECT system with 99technetiumm labelled hexemethylpropyleneamineoxime. 3. Sumatriptan had no effect on pulse, blood pressure or ECG indices. 4. All six volunteers experienced minor adverse effects during the intravenous infusion.

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Year:  1992        PMID： 1315562      PMCID： PMC1381329          DOI： 10.1111/j.1365-2125.1992.tb04058.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  6 in total

1.  The selective closure of feline carotid arteriovenous anastomoses (AVAs) by GR43175.

Authors:  M J Perren; W Feniuk; P P Humphrey
Journal:  Cephalalgia       Date:  1989       Impact factor: 6.292

2.  Migraine pain associated with middle cerebral artery dilatation: reversal by sumatriptan.

Authors:  L Friberg; J Olesen; H K Iversen; B Sperling
Journal:  Lancet       Date:  1991-07-06       Impact factor: 79.321

3.  The selective carotid arterial vasoconstrictor action of GR43175 in anaesthetized dogs.

Authors:  W Feniuk; P P Humphrey; M J Perren
Journal:  Br J Pharmacol       Date:  1989-01       Impact factor: 8.739

4.  Overview of initial clinical studies with intravenous and oral GR43175 in acute migraine.

Authors:  V L Perrin; M Färkkilä; J Goasguen; A Doenicke; J Brand; P Tfelt-Hansen
Journal:  Cephalalgia       Date:  1989       Impact factor: 6.292

5.  Lack of an interaction between propranolol and sumatriptan.

Authors:  A K Scott; T Walley; A M Breckenridge; L F Lacey; P A Fowler
Journal:  Br J Clin Pharmacol       Date:  1991-11       Impact factor: 4.335

6.  Focal hyperemia followed by spreading oligemia and impaired activation of rCBF in classic migraine.

Authors:  J Olesen; B Larsen; M Lauritzen
Journal:  Ann Neurol       Date:  1981-04       Impact factor: 10.422
  6 in total
  6 in total

1.  [PET and Doppler sonography in headaches].

Authors:  A May; C Weiller
Journal:  Schmerz       Date:  1996-06-17       Impact factor: 1.107

2.  Effects of sumatriptan on the cerebral intraparenchymal microcirculation in the cat.

Authors:  M Kobari; Y Fukuuchi; M Tomita; N Tanahashi; S Konno; H Takeda
Journal:  Br J Pharmacol       Date:  1993-12       Impact factor: 8.739

Review 3.  Sumatriptan. An updated review of its use in migraine.

Authors:  C M Perry; A Markham
Journal:  Drugs       Date:  1998-06       Impact factor: 9.546

Review 4.  Sumatriptan clinical pharmacokinetics.

Authors:  A K Scott
Journal:  Clin Pharmacokinet       Date:  1994-11       Impact factor: 6.447

Review 5.  Sumatriptan. A reappraisal of its pharmacology and therapeutic efficacy in the acute treatment of migraine and cluster headache.

Authors:  G L Plosker; D McTavish
Journal:  Drugs       Date:  1994-04       Impact factor: 9.546

Review 6.  Triptans and CGRP blockade - impact on the cranial vasculature.

Authors:  Silvia Benemei; Francesca Cortese; Alejandro Labastida-Ramírez; Francesca Marchese; Lanfranco Pellesi; Michele Romoli; Anne Luise Vollesen; Christian Lampl; Messoud Ashina
Journal:  J Headache Pain       Date:  2017-10-10       Impact factor: 7.277
  6 in total

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