Literature DB >> 1314589

Molecular cloning and binding properties of the human type II activin receptor.

C J Donaldson1, L S Mathews, W W Vale.   

Abstract

A full-length cDNA for the type II human activin receptor was cloned by hybridization from a human testis cDNA library. The sequence encodes a 513 amino acid protein that is 99% identical, at the amino acid level, with the mouse type II activin receptor. The type II human activin receptor consists of an extracellular domain that specifically binds activin A with a Kd of 360 pM, a single-membrane spanning domain, and an intracellular kinase domain with predicted serine/threonine specificity.

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Year:  1992        PMID： 1314589     DOI： 10.1016/0006-291x(92)91194-u

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  15 in total

1.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1992-07-25       Impact factor: 16.971

2.  A chimeric serine/threonine kinase receptor system reveals the potential of multiple type II receptors to cooperate with transforming growth factor-beta type I receptor.

Authors:  M Muramatsu; J Yan; K Eto; T Tomoda; R Yamada; K Arai
Journal:  Mol Biol Cell       Date:  1997-03       Impact factor: 4.138

Review 3.  Genes involved in testicular development and function.

Authors:  D J Lamb
Journal:  World J Urol       Date:  1995       Impact factor: 4.226

4.  Expression and localization of inhibin/activin subunits and activin receptors in MCF-7 cells, a human breast cancer cell line.

Authors:  S Y Ying; Z Zhang
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

5.  Association between the candidate susceptibility gene ACVR2A on chromosome 2q22 and pre-eclampsia in a large Norwegian population-based study (the HUNT study).

Authors:  Linda T Roten; Matthew P Johnson; Siri Forsmo; Elizabeth Fitzpatrick; Thomas D Dyer; Shaun P Brennecke; John Blangero; Eric K Moses; Rigmor Austgulen
Journal:  Eur J Hum Genet       Date:  2008-09-10       Impact factor: 4.246

6.  Expression and localization of inhibin/activin and activin receptors in GH3 cells, a rat pituitary adenocarcinoma cell line.

Authors:  C Ying; Z Zhang; G Huang; S Q Li; S Y Ying
Journal:  J Endocrinol Invest       Date:  1996-01       Impact factor: 4.256

7.  Crystal structure of activin receptor type IIB kinase domain from human at 2.0 Angstrom resolution.

Authors:  Seungil Han; Pat Loulakis; Matt Griffor; Zhi Xie
Journal:  Protein Sci       Date:  2007-10       Impact factor: 6.725

8.  A molecular study of synovial chondromatosis.

Authors:  Narasimhan P Agaram; Lei Zhang; Brendan C Dickson; David Swanson; Yun-Shao Sung; David M Panicek; Meera Hameed; John H Healey; Cristina R Antonescu
Journal:  Genes Chromosomes Cancer       Date:  2019-10-18       Impact factor: 5.006

9.  A genetic variant in microRNA target site of TGF-β signaling pathway increases the risk of colorectal cancer in a Chinese population.

Authors:  Jing Gong; Na Shen; Hong-Mei Zhang; Rong Zhong; Wei Chen; Xiaoping Miao; An-Yuan Guo
Journal:  Tumour Biol       Date:  2013-12-29

10.  Human testicular germ cell tumours express inhibin subunits, activin receptors and follistatin mRNAs.

Authors:  R H van Schaik; C D Wierikx; L H Looijenga; J W Oosterhuis; F H de Jong
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640
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