Literature DB >> 1314424

Lithium-sensitive production of inositol phosphates during amphibian embryonic mesoderm induction.

J A Maslanski1, L Leshko, W B Busa.   

Abstract

Mesoderm induction and body axis determination in frog (Xenopus) embryos are thought to involve growth factor-mediated cell-cell signaling, but the signal transduction pathways are unknown. Li+, which inhibits the polyphosphoinositide (PI) cycle signal transduction pathway in many cells, also disrupts axis determination and mesoderm induction. Amounts of the PI cycle-derived second messenger, inositol 1,4,5-trisphosphate, increased during mesoderm induction in normal embryos; addition of Li+ inhibited the embryonic inositol monophosphatase and reversed this increase. Embryonic PI cycle activity thus shows characteristics that indicate it may function in mesoderm induction and axis determination.

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Year:  1992        PMID： 1314424     DOI： 10.1126/science.1314424

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  15 in total

1.  Statistical evaluation of differential expression on cDNA nylon arrays with replicated experiments.

Authors:  R Herwig; P Aanstad; M Clark; H Lehrach
Journal:  Nucleic Acids Res       Date:  2001-12-01       Impact factor: 16.971

Review 2.  Calcium at fertilization and in early development.

Authors:  Michael Whitaker
Journal:  Physiol Rev       Date:  2006-01       Impact factor: 37.312

3.  Direct activation of phospholipase C-gamma by fibroblast growth factor receptor is not required for mesoderm induction in Xenopus animal caps.

Authors:  A J Muslin; K G Peters; L T Williams
Journal:  Mol Cell Biol       Date:  1994-05       Impact factor: 4.272

4.  Plant inositol monophosphatase is a lithium-sensitive enzyme encoded by a multigene family.

Authors:  G E Gillaspy; J S Keddie; K Oda; W Gruissem
Journal:  Plant Cell       Date:  1995-12       Impact factor: 11.277

5.  A mutation in PLC1, a candidate phosphoinositide-specific phospholipase C gene from Saccharomyces cerevisiae, causes aberrant mitotic chromosome segregation.

Authors:  W E Payne; M Fitzgerald-Hayes
Journal:  Mol Cell Biol       Date:  1993-07       Impact factor: 4.272

Review 6.  Calcium signaling in vertebrate embryonic patterning and morphogenesis.

Authors:  Diane C Slusarski; Francisco Pelegri
Journal:  Dev Biol       Date:  2007-05-03       Impact factor: 3.582

Review 7.  Calcium dynamics integrated into signalling pathways that influence vertebrate axial patterning.

Authors:  Christina M Freisinger; Igor Schneider; Trudi A Westfall; Diane C Slusarski
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2008-04-12       Impact factor: 6.237

8.  Inositol 1,4,5-trisphosphate mass changes from fertilization through first cleavage in Xenopus laevis.

Authors:  B J Stith; M Goalstone; S Silva; C Jaynes
Journal:  Mol Biol Cell       Date:  1993-04       Impact factor: 4.138

9.  Cell-autonomous expression and position-dependent repression by Li+ of two zygotic genes during sea urchin early development.

Authors:  C Ghiglione; G Lhomond; T Lepage; C Gache
Journal:  EMBO J       Date:  1993-01       Impact factor: 11.598

10.  Synaptic polarity depends on phosphatidylinositol signaling regulated by myo-inositol monophosphatase in Caenorhabditis elegans.

Authors:  Tsubasa Kimata; Yoshinori Tanizawa; Yoko Can; Shingo Ikeda; Atsushi Kuhara; Ikue Mori
Journal:  Genetics       Date:  2012-03-23       Impact factor: 4.562
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