Literature DB >> 1314212

Lacidipine: a dihydropyridine calcium antagonist with antioxidant activity.

F T van Amsterdam1, A Roveri, M Maiorino, E Ratti, F Ursini.   

Abstract

Lacidipine, a new, long-acting antihypertensive dihydropyridine calcium antagonist was tested for potential antioxidant effect in a series of tests that consider specific radical species. A direct quenching of several radical species could be measured. Moreover, in biological membranes deriving from rat brain tissue, lacidipine showed an activity comparable to reference antioxidant compounds like vitamin E.

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Year:  1992        PMID: 1314212     DOI: 10.1016/0891-5849(92)90025-c

Source DB:  PubMed          Journal:  Free Radic Biol Med        ISSN: 0891-5849            Impact factor:   7.376


  16 in total

1.  Inhibition of LDL oxidation and oxidized LDL-induced cytotoxicity by dihydropyridine calcium antagonists.

Authors:  A Sevanian; L Shen; F Ursini
Journal:  Pharm Res       Date:  2000-08       Impact factor: 4.200

Review 2.  Endothelial dysfunction: a strategic target in the treatment of hypertension?

Authors:  Eva H C Tang; Paul M Vanhoutte
Journal:  Pflugers Arch       Date:  2010-02-02       Impact factor: 3.657

3.  Characterization and in vitro biological activities of Thai traditional fermented shrimp pastes.

Authors:  Thanyaporn Kleekayai; Donlaporn Saetae; Ongart Wattanachaiyingyong; Shinjiro Tachibana; Masaaki Yasuda; Worapot Suntornsuk
Journal:  J Food Sci Technol       Date:  2014-09-06       Impact factor: 2.701

Review 4.  Dihydropyridine calcium channel blockers and renal disease.

Authors:  Nicolás R Robles; Francesco Fici; Guido Grassi
Journal:  Hypertens Res       Date:  2016-07-14       Impact factor: 3.872

5.  Lacidipine attenuates reserpine-induced depression-like behavior and oxido-nitrosative stress in mice.

Authors:  Kunal Khurana; Nitin Bansal
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2019-06-11       Impact factor: 3.000

Review 6.  Dual mode of action of dihydropyridine calcium antagonists: a role for nitric oxide.

Authors:  S Dhein; A Salameh; R Berkels; W Klaus
Journal:  Drugs       Date:  1999-09       Impact factor: 9.546

7.  Action of the calcium channel blocker lacidipine on cardiac hypertrophy and endothelin-1 gene expression in stroke-prone hypertensive rats.

Authors:  O Feron; S Salomone; T Godfraind
Journal:  Br J Pharmacol       Date:  1996-06       Impact factor: 8.739

8.  Investigation of effects of Lacidipine, Ramipril and Valsartan on DNA damage and oxidative stress occurred in acute and chronic periods following isoproterenol-induced myocardial infarct in rats.

Authors:  Mevlut Sait Keles; Yasin Bayir; Halis Suleyman; Zekai Halici
Journal:  Mol Cell Biochem       Date:  2009-03-19       Impact factor: 3.396

9.  Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.

Authors:  M E Ortiz; L J Núñez-Vergara; C Camargo; J A Squella
Journal:  Pharm Res       Date:  2004-03       Impact factor: 4.200

10.  Studies on efficient production of a novel l-asparaginase by a newly isolated Pseudomonas resinovorans IGS-131 and its heterologous expression in Escherichia coli.

Authors:  Kanti N Mihooliya; Jitender Nandal; Alka Kumari; Sidhanta Nanda; Himanshu Verma; Debendra K Sahoo
Journal:  3 Biotech       Date:  2020-03-02       Impact factor: 2.406

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