Literature DB >> 1313896

Association of ICP0 but not ICP27 with purified virions of herpes simplex virus type 1.

F Yao1, R J Courtney.   

Abstract

Recent studies have shown that ICP4, one of the major immediate-early proteins of herpes simplex virus type 1 is present within the tegument region of the virion (F. Yao and R. J. Courtney, J. Virol. 63:3338-3344, 1989). With monoclonal antibodies to two additional immediate-early proteins, ICP0 and ICP27, and Western blot (immunoblot) analysis, ICP0, but not ICP27, was also found to be associated with purified virus particles. In an effort to localize the ICP0 within the virion, purified virions were treated with trypsin in the presence and absence of detergent. The data suggest that ICP0 is located within the tegument region of the virion and is not localized in the envelope or within the nucleocapsid. The number of molecules of ICP0 per virion was estimated to be approximately 150.

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Year:  1992        PMID： 1313896      PMCID： PMC241025     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  51 in total

1.  Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions.

Authors:  M P Quinlan; D M Knipe
Journal:  Mol Cell Biol       Date:  1985-05       Impact factor: 4.272

2.  Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation.

Authors:  P O'Hare; G S Hayward
Journal:  J Virol       Date:  1985-12       Impact factor: 5.103

3.  A mutant herpesvirus protein leads to a block in nuclear localization of other viral proteins.

Authors:  D M Knipe; J L Smith
Journal:  Mol Cell Biol       Date:  1986-07       Impact factor: 4.272

4.  Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture.

Authors:  W R Sacks; P A Schaffer
Journal:  J Virol       Date:  1987-03       Impact factor: 5.103

5.  Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins.

Authors:  R W Honess; B Roizman
Journal:  J Virol       Date:  1974-07       Impact factor: 5.103

6.  A temperature-sensitive mutant of herpes simplex virus type 1 defective in the synthesis of the major capsid polypeptide.

Authors:  D R Bone; R J Courtney
Journal:  J Gen Virol       Date:  1974-07       Impact factor: 3.891

7.  Isolation and characterization of a large molecular-weight polypeptide of herpes simplex virus type 1.

Authors:  R J Courtney; M Benyesh-Melnick
Journal:  Virology       Date:  1974-12       Impact factor: 3.616

8.  Proteins specified by herpes simplex virus. V. Purification and structural proteins of the herpesvirion.

Authors:  P G Spear; B Roizman
Journal:  J Virol       Date:  1972-01       Impact factor: 5.103

9.  Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110.

Authors:  N D Stow; E C Stow
Journal:  J Gen Virol       Date:  1986-12       Impact factor: 3.891

10.  Characterization of the IE110 gene of herpes simplex virus type 1.

Authors:  L J Perry; F J Rixon; R D Everett; M C Frame; D J McGeoch
Journal:  J Gen Virol       Date:  1986-11       Impact factor: 3.891
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  50 in total

1.  Glycoprotein K specified by herpes simplex virus type 1 is expressed on virions as a Golgi complex-dependent glycosylated species and functions in virion entry.

Authors:  T P Foster; G V Rybachuk; K G Kousoulas
Journal:  J Virol       Date:  2001-12       Impact factor: 5.103

Review 2.  Herpesvirus assembly and egress.

Authors:  Thomas C Mettenleiter
Journal:  J Virol       Date:  2002-02       Impact factor: 5.103

3.  Truncation of the C-terminal acidic transcriptional activation domain of herpes simplex virus VP16 renders expression of the immediate-early genes almost entirely dependent on ICP0.

Authors:  K L Mossman; J R Smiley
Journal:  J Virol       Date:  1999-12       Impact factor: 5.103

Review 4.  Herpesvirus lytic replication and the cell cycle: arresting new developments.

Authors:  E K Flemington
Journal:  J Virol       Date:  2001-05       Impact factor: 5.103

5.  In rat dorsal root ganglion neurons, herpes simplex virus type 1 tegument forms in the cytoplasm of the cell body.

Authors:  Monica Miranda-Saksena; Ross A Boadle; Patricia Armati; Anthony L Cunningham
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

6.  Recruitment of herpes simplex virus type 1 immediate-early protein ICP0 to the virus particle.

Authors:  Kevin Maringer; Gillian Elliott
Journal:  J Virol       Date:  2010-02-17       Impact factor: 5.103

Review 7.  Herpesvirus transport to the nervous system and back again.

Authors:  Gregory Smith
Journal:  Annu Rev Microbiol       Date:  2012-06-15       Impact factor: 15.500

8.  Deletion of the herpes simplex virus VP22-encoding gene (UL49) alters the expression, localization, and virion incorporation of ICP0.

Authors:  Gillian Elliott; Wali Hafezi; Alison Whiteley; Emmanuelle Bernard
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

9.  The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection.

Authors:  M A Hardwicke; R M Sandri-Goldin
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

10.  Human cytomegalovirus UL76 encodes a novel virion-associated protein that is able to inhibit viral replication.

Authors:  Shang-Kwei Wang; Chang-Yih Duh; Cheng-Wen Wu
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103
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