| Literature DB >> 1313408 |
Y Matsuno1, K Mukai, H Uhara, I Akao, S Furuya, Y Sato, S Hirohashi, Y Shimosato.
Abstract
Epstein-Barr virus DNA was detected in a case of lymphoepithelioma-like thymic carcinoma. A homogeneous terminal structure of the viral DNA was demonstrated in this case, indicating the presence of the viral genome in clonally expanded tumor cells. Since all of 26 other thymic epithelial tumors (eight non-invasive, 13 invasive thymomas and four non-lymphoepithelioma-like thymic carcinomas) in Japanese were negative by polymerase chain reaction, it is suggested that lymphoepithelioma-like thymic carcinoma may represent a unique pathological entity distinct from Epstein-Barr virus-negative thymic epithelial tumors, which are in the majority in Japan.Entities:
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Year: 1992 PMID： 1313408 PMCID： PMC5918789 DOI： 10.1111/j.1349-7006.1992.tb00075.x
Source DB: PubMed Journal: Jpn J Cancer Res ISSN： 0910-5050