Literature DB >> 13129936

AcrB multidrug efflux pump of Escherichia coli: composite substrate-binding cavity of exceptional flexibility generates its extremely wide substrate specificity.

Edward W Yu1, Julio R Aires, Hiroshi Nikaido.   

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Year:  2003        PMID： 13129936      PMCID： PMC193975          DOI： 10.1128/JB.185.19.5657-5664.2003

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


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  47 in total

1.  A new ABC transporter mediating the detachment of lipid-modified proteins from membranes.

Authors:  T Yakushi; K Masuda; S Narita; S Matsuyama; H Tokuda
Journal:  Nat Cell Biol       Date:  2000-04       Impact factor: 28.824

2.  Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export.

Authors:  V Koronakis; A Sharff; E Koronakis; B Luisi; C Hughes
Journal:  Nature       Date:  2000-06-22       Impact factor: 49.962

3.  Structural mechanisms of QacR induction and multidrug recognition.

Authors:  M A Schumacher; M C Miller; S Grkovic; M H Brown; R A Skurray; R G Brennan
Journal:  Science       Date:  2001-12-07       Impact factor: 47.728

4.  Structural basis of gating by the outer membrane transporter FecA.

Authors:  Andrew D Ferguson; Ranjan Chakraborty; Barbara S Smith; Lothar Esser; Dick van der Helm; Johann Deisenhofer
Journal:  Science       Date:  2002-03-01       Impact factor: 47.728

5.  Crystal structure of bacterial multidrug efflux transporter AcrB.

Authors:  Satoshi Murakami; Ryosuke Nakashima; Eiki Yamashita; Akihito Yamaguchi
Journal:  Nature       Date:  2002-10-10       Impact factor: 49.962

Review 6.  Mystery of multidrug transporters: the answer can be simple.

Authors:  Alex A Neyfakh
Journal:  Mol Microbiol       Date:  2002-06       Impact factor: 3.501

Review 7.  Structural mechanisms of multidrug recognition and regulation by bacterial multidrug transcription factors.

Authors:  Maria A Schumacher; Richard G Brennan
Journal:  Mol Microbiol       Date:  2002-08       Impact factor: 3.501

8.  The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism.

Authors:  Kaspar P Locher; Allen T Lee; Douglas C Rees
Journal:  Science       Date:  2002-05-10       Impact factor: 47.728

9.  Lipid-layer crystallization and preliminary three-dimensional structural analysis of AcrA, the periplasmic component of a bacterial multidrug efflux pump.

Authors:  A J Avila-Sakar; S Misaghi; E M Wilson-Kubalek; K H Downing; H Zgurskaya; H Nikaido; E Nogales
Journal:  J Struct Biol       Date:  2001-10       Impact factor: 2.867

Review 10.  Multidrug transporters and antibiotic resistance in Lactococcus lactis.

Authors:  Gerrit J Poelarends; Piotr Mazurkiewicz; Wil N Konings
Journal:  Biochim Biophys Acta       Date:  2002-09-10
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  62 in total

Review 1.  Molecular basis of bacterial outer membrane permeability revisited.

Authors:  Hiroshi Nikaido
Journal:  Microbiol Mol Biol Rev       Date:  2003-12       Impact factor: 11.056

2.  TtgV bound to a complex operator site represses transcription of the promoter for the multidrug and solvent extrusion TtgGHI pump.

Authors:  María-Eugenia Guazzaroni; Wilson Terán; Xiaodong Zhang; María-Trinidad Gallegos; Juan L Ramos
Journal:  J Bacteriol       Date:  2004-05       Impact factor: 3.490

Review 3.  Understanding the structural mechanisms of antibiotic resistance sets the platform for new discovery.

Authors:  Stephanie M Reeve; Michael N Lombardo; Amy C Anderson
Journal:  Future Microbiol       Date:  2015-10-30       Impact factor: 3.165

4.  Characterization of a resistance-nodulation-cell division transporter system associated with the syr-syp genomic island of Pseudomonas syringae pv. syringae.

Authors:  Hyojeung Kang; Dennis C Gross
Journal:  Appl Environ Microbiol       Date:  2005-09       Impact factor: 4.792

5.  Interaction between the TolC and AcrA proteins of a multidrug efflux system of Escherichia coli.

Authors:  Fasahath Husain; Matthew Humbard; Rajeev Misra
Journal:  J Bacteriol       Date:  2004-12       Impact factor: 3.490

Review 6.  Vacuuming the periplasm.

Authors:  Olga Lomovskaya; Maxim Totrov
Journal:  J Bacteriol       Date:  2005-03       Impact factor: 3.490

7.  Dynamics of the trimeric AcrB transporter protein inferred from a B-factor analysis of the crystal structure.

Authors:  W C Lu; C Z Wang; E W Yu; K M Ho
Journal:  Proteins       Date:  2006-01-01

8.  Aminoglycosides are captured from both periplasm and cytoplasm by the AcrD multidrug efflux transporter of Escherichia coli.

Authors:  Julio Ramos Aires; Hiroshi Nikaido
Journal:  J Bacteriol       Date:  2005-03       Impact factor: 3.490

9.  AcrAB-TolC directs efflux-mediated multidrug resistance in Salmonella enterica serovar typhimurium DT104.

Authors:  Sylvie Baucheron; Shaun Tyler; David Boyd; Michael R Mulvey; Elisabeth Chaslus-Dancla; Axel Cloeckaert
Journal:  Antimicrob Agents Chemother       Date:  2004-10       Impact factor: 5.191

10.  Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein.

Authors:  Maria A Schumacher; Marshall C Miller; Richard G Brennan
Journal:  EMBO J       Date:  2004-07-15       Impact factor: 11.598
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