Xue-feng Wang1, Miao-qing Zhao. 1. Department of Obstetrics and Gynecology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China. douwangx-uefeng@163.com
Abstract
OBJECTIVE: To compare the clinical effects of ligustrazine and Salvia miltiorrhiza injection solutions in the complementary therapy of pregnancy-induced hypertension (PIH). METHODS:Sixty patients with PIH were equally divided into 2 groups to receive intravenous infusion of 80 mg ligustrazine and 16 ml Salvia miltiorrhiza injection solution respectively, in addition to the conventional therapies. The effects of the two complementary treatments were compared. RESULTS: After a treatment course of 10 days, ligustrazine produced obvious effect in inhibiting fibrinolysis and promoting microcirculation of the patients. Salvia miltiorrhiza injection resulted in obvious reduction of blood viscosity, cholesterol and lipoprotein. CONCLUSION:Ligustrazine and Salvia miltiorrhiza injections produce obvious therapeutic effects on PIH, but they are used for different clinical purposes as their in pharmacological action difference.
RCT Entities:
OBJECTIVE: To compare the clinical effects of ligustrazine and Salvia miltiorrhiza injection solutions in the complementary therapy of pregnancy-induced hypertension (PIH). METHODS: Sixty patients with PIH were equally divided into 2 groups to receive intravenous infusion of 80 mg ligustrazine and 16 ml Salvia miltiorrhiza injection solution respectively, in addition to the conventional therapies. The effects of the two complementary treatments were compared. RESULTS: After a treatment course of 10 days, ligustrazine produced obvious effect in inhibiting fibrinolysis and promoting microcirculation of the patients. Salvia miltiorrhiza injection resulted in obvious reduction of blood viscosity, cholesterol and lipoprotein. CONCLUSION:Ligustrazine and Salvia miltiorrhiza injections produce obvious therapeutic effects on PIH, but they are used for different clinical purposes as their in pharmacological action difference.
Authors: Xinhua Zhou; Guozhen Cui; Hisa Hui Ling Tseng; Simon Ming-Yuen Lee; George Pak Heng Leung; Shun Wan Chan; Yiu Wa Kwan; Maggie Pui Man Hoi Journal: Evid Based Complement Alternat Med Date: 2016-11-23 Impact factor: 2.629