Literature DB >> 1311490

Induction of anti-viral immune responses by immunization with recombinant-DNA encoded avian coronavirus nucleocapsid protein.

A M Boots1, B J Benaissa-Trouw, W Hesselink, E Rijke, C Schrier, E J Hensen.   

Abstract

Immune responses to the infectious bronchitis virus (IBV) nucleocapsid protein were studied using a recombinant-DNA expression product. In mice, a lymphocyte proliferative response and a delayed-type hypersensitivity reaction to IBV were induced upon immunization with this nucleocapsid protein. Next, we studied the role of the expressed nucleocapsid protein in induction of a protective immune response to IBV in chickens. Chickens were primed with nucleocapsid protein and subsequently boosted with inactivated IBV, strain M41. Proliferative responses of blood mononuclear cells corresponded with increased mean haemagglutination inhibition and virus neutralization titres. Finally, an increased tracheal protection against challenge with live IBV was observed. These results indicate that infectious bronchitis virus nucleocapsid protein is a relevant target for immune recognition in both the mouse and the chicken.

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Year:  1992        PMID： 1311490      PMCID： PMC7131429          DOI： 10.1016/0264-410x(92)90028-i

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  32 in total

1.  Presence of viral antigens and antibody in the trachea of chickens infected with avian infectious bronchitis virus.

Authors:  R A Hawkes; J H Darbyshire; R W Peters; A P Mockett; D Cavanagh
Journal:  Avian Pathol       Date:  1983       Impact factor: 3.378

2.  Coronavirus IBV: further evidence that the surface projections are associated with two glycopolypeptides.

Authors:  D Cavanagh
Journal:  J Gen Virol       Date:  1983-08       Impact factor: 3.891

3.  Molecular epidemiology of infectious bronchitis virus in The Netherlands.

Authors:  J G Kusters; H G Niesters; N M Bleumink-Pluym; F G Davelaar; M C Horzinek; B A Van der Zeijst
Journal:  J Gen Virol       Date:  1987-02       Impact factor: 3.891

4.  Identification of a DTH-inducing T-cell epitope on the E2 membrane protein of Semliki Forest virus.

Authors:  A Snijders; B J Benaissa-Trouw; J D Oosting; H Snippe; C A Kraaijeveld
Journal:  Cell Immunol       Date:  1989-10-01       Impact factor: 4.868

5.  Coronavirus multiplication: locations of genes for virion proteins on the avian infectious bronchitis virus genome.

Authors:  D F Stern; B M Sefton
Journal:  J Virol       Date:  1984-04       Impact factor: 5.103

6.  Cytotoxic T cell recognition of the influenza nucleoprotein and hemagglutinin expressed in transfected mouse L cells.

Authors:  A R Townsend; A J McMichael; N P Carter; J A Huddleston; G G Brownlee
Journal:  Cell       Date:  1984-11       Impact factor: 41.582

7.  Rapid detection and identification of avian infectious bronchitis virus.

Authors:  K A Zwaagstra; B A van der Zeijst; J G Kusters
Journal:  J Clin Microbiol       Date:  1992-01       Impact factor: 5.948

8.  Cell mediated and humoral immune response of chickens to inactivated oil-emulsion infectious bronchitis vaccine.

Authors:  L M Timms; C D Bracewell
Journal:  Res Vet Sci       Date:  1983-03       Impact factor: 2.534

9.  Protection against hepatitis B virus infection by immunization with hepatitis B core antigen.

Authors:  S Iwarson; E Tabor; H C Thomas; P Snoy; R J Gerety
Journal:  Gastroenterology       Date:  1985-03       Impact factor: 22.682

10.  Construction of a new family of high efficiency bacterial expression vectors: identification of cDNA clones coding for human liver proteins.

Authors:  K K Stanley; J P Luzio
Journal:  EMBO J       Date:  1984-06       Impact factor: 11.598
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  20 in total

1.  Mapping of antigenic sites on the nucleocapsid protein of the severe acute respiratory syndrome coronavirus.

Authors:  Yuxian He; Yusen Zhou; Hao Wu; Zhihua Kou; Shuwen Liu; Shibo Jiang
Journal:  J Clin Microbiol       Date:  2004-11       Impact factor: 5.948

2.  Oral and nasal DNA vaccines delivered by attenuated Salmonella enterica serovar Typhimurium induce a protective immune response against infectious bronchitis in chickens.

Authors:  Hongmei Jiao; Zhiming Pan; Yuelan Yin; Shizhong Geng; Lin Sun; Xinan Jiao
Journal:  Clin Vaccine Immunol       Date:  2011-05-18

3.  The S1 glycoprotein but not the N or M proteins of avian infectious bronchitis virus induces protection in vaccinated chickens.

Authors:  J Ignjatovic; L Galli
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574

4.  A combined nucleocapsid vaccine induces vigorous SARS-CD8+ T-cell immune responses.

Authors:  Ali Azizi; Susan Aucoin; Helina Tadesse; Rita Frost; Masoud Ghorbani; Catalina Soare; Turaya Naas; Francisco Diaz-Mitoma
Journal:  Genet Vaccines Ther       Date:  2005-08-22

5.  Safety and efficacy of an attenuated Chinese QX-like infectious bronchitis virus strain as a candidate vaccine.

Authors:  Ye Zhao; Jin-long Cheng; Xiao-yu Liu; Jing Zhao; Yan-xin Hu; Guo-zhong Zhang
Journal:  Vet Microbiol       Date:  2015-08-05       Impact factor: 3.293

6.  Comparative genomics of Korean infectious bronchitis viruses (IBVs) and an animal model to evaluate pathogenicity of IBVs to the reproductive organs.

Authors:  Seung-Min Hong; Hyuk-Joon Kwon; Il-Hwan Kim; Mei-Lan Mo; Jae-Hong Kim
Journal:  Viruses       Date:  2012-10-30       Impact factor: 5.048

7.  Altered pathogenicity, immunogenicity, tissue tropism and 3'-7kb region sequence of an avian infectious bronchitis coronavirus strain after serial passage in embryos.

Authors:  Shengwang Liu; Xiaonan Zhang; Liyang Gong; Baolong Yan; Chengren Li; Zongxi Han; Yuhao Shao; Huixin Li; Xiangang Kong
Journal:  Vaccine       Date:  2009-06-11       Impact factor: 3.641

8.  Infectious bronchitis virus: Immunopathogenesis of infection in the chicken.

Authors:  G D Raj; R C Jones
Journal:  Avian Pathol       Date:  1997       Impact factor: 3.378

9.  A novel variant of avian infectious bronchitis virus resulting from recombination among three different strains.

Authors:  W Jia; K Karaca; C R Parrish; S A Naqi
Journal:  Arch Virol       Date:  1995       Impact factor: 2.574

Review 10.  Severe acute respiratory syndrome vaccine development: experiences of vaccination against avian infectious bronchitis coronavirus.

Authors:  Dave Cavanagh
Journal:  Avian Pathol       Date:  2003-12       Impact factor: 3.378
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