| Literature DB >> 1309642 |
Abstract
Follicular dendritic cells (FDC) are involved in the trapping and retention of antigen-antibody complexes in lymphoid follicles. This FDC immobilized antigen is thought to be involved in the generation of memory B-lymphocytes. Follicular trapping of both Aleutian disease virus and HIV particles has been demonstrated. However as far as known their affects on FDC and follicular B-cells are completely different. It is hypothesized that the trapping of (antibody-complexed) virus particles by the FDC-network may have an important role in several virus diseases.Entities:
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Year: 1992 PMID: 1309642 DOI: 10.1007/bf01321130
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574