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Literature DB >> 13094506

The physiology of iodine.

Abstract

The history of work on the physiology of iodine is traced, and the rapid advances of the past quarter of a century described. In considering the application of these discoveries and of recently-developed techniques to problems of thyroid function and the treatment of hyperthyroidism, the author examines the mechanism of the iodide trap and the role of iodide in the biosynthesis of hormones. The kinetics of hormone release, the nature of the circulating thyroid hormone, and hormonal metabolism are discussed.

Entities: Chemical Disease

Keywords: IODINE/metabolism; THYROID GLAND/physiology; THYROXIN

Mesh：

Substances：
Iodine
Thyroxine

Year: 1953 PMID： 13094506 PMCID： PMC2542103

Source DB: PubMed Journal: Bull World Health Organ ISSN： 0042-9686 Impact factor: 9.408

17 in total

The physiology of iodine.

1. Chemistry of Thyroxine: Constitution and Synthesis of Thyroxine.

2. The iodine-deficient human thyroid gland; a preliminary report.

3. Effect of 3:5:3'-L-triiodothyronine in myxoedema.

4. The identification of 3:5:3'-L-triiodothyronine in human plasma.

5. The effect of hypophysectomy on the biologic decay of thyroidal radioiodine.

6. Protein-bound iodine in infants from birth to one year of age.

7. Cretinism with goiter; a case report.

8. Effect of iodide, thiouracil and thyroxine on the disappearance of thyroidal I131.

9. Labeled sulfur uptake by thyroids of rats with low plasma thiocyanate levels.

10. Mucolytic activity of the thyroid gland.

Review 1. The Na+/I- symporter (NIS): mechanism and medical impact.