Literature DB >> 1307489

Interleukin 10: an overview.

D Rennick1, D Berg, G Holland.   

Abstract

Since the original description of interleukin-10, a wealth of information concerning its biological properties has been gathered. Studies in vitro have rapidly identified both immunostimulatory and immunosuppressive activities for IL-10. Based on these findings, in vivo studies were initiated in a variety of animal disease models to assess the importance of these activities. This review will summarize the pleiotropic properties of IL-10 and will survey current research regarding the potential of IL-10 to regulate acute and chronic inflammatory reactions.

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Year:  1992        PMID: 1307489     DOI: 10.1016/0955-2235(92)90020-i

Source DB:  PubMed          Journal:  Prog Growth Factor Res        ISSN: 0955-2235


  14 in total

1.  Inflammatory response to a porcine membrane composed of fibrous collagen and elastin as dermal substitute.

Authors:  B Klein; R Schiffer; B Hafemann; B Klosterhalfen; G Zwadlo-Klarwasser
Journal:  J Mater Sci Mater Med       Date:  2001-05       Impact factor: 3.896

2.  Th1 (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE).

Authors:  J F Viallard; J L Pellegrin; V Ranchin; T Schaeverbeke; J Dehais; M Longy-Boursier; J M Ragnaud; B Leng; J F Moreau
Journal:  Clin Exp Immunol       Date:  1999-01       Impact factor: 4.330

3.  Gastric mucosal secretion of interleukin-10: relations to histopathology, Helicobacter pylori status, and tumour necrosis factor-alpha secretion.

Authors:  K Bodger; J I Wyatt; R V Heatley
Journal:  Gut       Date:  1997-06       Impact factor: 23.059

Review 4.  Mechanisms of innate resistance to Toxoplasma gondii infection.

Authors:  J Alexander; T M Scharton-Kersten; G Yap; C W Roberts; F Y Liew; A Sher
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1997-09-29       Impact factor: 6.237

5.  Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii.

Authors:  L E Neyer; G Grunig; M Fort; J S Remington; D Rennick; C A Hunter
Journal:  Infect Immun       Date:  1997-05       Impact factor: 3.441

6.  Blockade of costimulation prevents infection-induced immunopathology in interleukin-10-deficient mice.

Authors:  E N Villegas; U Wille; L Craig; P S Linsley; D M Rennick; R Peach; C A Hunter
Journal:  Infect Immun       Date:  2000-05       Impact factor: 3.441

7.  IL-10 Enhances IgE-Mediated Mast Cell Responses and Is Essential for the Development of Experimental Food Allergy in IL-10-Deficient Mice.

Authors:  Stephanie H Polukort; Jeffrey Rovatti; Logan Carlson; Chelsea Thompson; Jennifer Ser-Dolansky; Shannon R M Kinney; Sallie S Schneider; Clinton B Mathias
Journal:  J Immunol       Date:  2016-05-06       Impact factor: 5.422

8.  Local interleukin-10 production during respiratory syncytial virus bronchiolitis is associated with post-bronchiolitis wheeze.

Authors:  Annemieke Schuurhof; Riny Janssen; Hanneke de Groot; Hennie M Hodemaekers; Arja de Klerk; Jan Ll Kimpen; Louis Bont
Journal:  Respir Res       Date:  2011-09-12

9.  Transcriptional characteristics of CD4 T cells in young asthmatic children: RORC and FOXP3 axis.

Authors:  Agnes Hamzaoui; Haïfa Maalmi; Anissa Berraïes; Hanadi Abid; Jamel Ammar; Kamel Hamzaoui
Journal:  J Inflamm Res       Date:  2011-11-11

10.  IL-10 signaling blockade controls murine West Nile virus infection.

Authors:  Fengwei Bai; Terrence Town; Feng Qian; Penghua Wang; Masahito Kamanaka; Tarah M Connolly; David Gate; Ruth R Montgomery; Richard A Flavell; Erol Fikrig
Journal:  PLoS Pathog       Date:  2009-10-09       Impact factor: 6.823

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