Literature DB >> 13066702

Proguanil, the isolation of a metabolite with high antimalarial activity.

A F CROWTHER, A A LEVI.   

Abstract

Entities:  

Keywords:  CHLOROGUANIDE/metabolism

Mesh：

Substances：

Year:  1953        PMID： 13066702      PMCID： PMC1509229          DOI： 10.1111/j.1476-5381.1953.tb00758.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


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  5 in total

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5.  Effect of 2,4-diamino-5-(p-chlorophenoxy)-6-methylpyrimidine and 2,4-diamino-6,7-diphenylpteridine on chloroguanide-resistant strain of Plasmodium gallinaceum.

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2.  The inhibitory action of some antimalarial drugs and related compounds on the hexokinase of yeast and of Plasmodium berghei.

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Journal:  Br J Pharmacol Chemother       Date:  1957-03

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Authors:  D ROBINSON; J N SMITH; R T WILLIAMS
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5.  A mechanism for the synergistic antimalarial action of atovaquone and proguanil.

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6.  Design, synthesis and biological evaluation of antimalarial activity of new derivatives of 2,4,6-s-triazine.

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