Gamma globulin; status of availability for prevention of poliomyelitis.

A limited and temporary preventive effect has been noted for gamma globulin used under certain conditions. There is available a supply of gamma globulin which is inadequate to meet the demand with the methods of use indicated in the light of present knowledge. All supplies of gamma globulin have been placed under the responsibility of the Office of Defense Mobilization. Supplies allocated to the state of California are being made available to physicians through their local health departments on the basis of past and current incidence of poliomyelitis for use in protecting persons in household contact with patients with diagnosed cases. The most effective use of California's allocation of this material can be expected to prevent or modify approximately 40 cases on the basis of the past five-year experience (1947-1951). Parents, physicians and health officials must know the facts and cooperate to make the best of a difficult situation.