| Literature DB >> 1304338 |
I Kracun1, S Kalanj, J Talan-Hranilovic, C Cosovic.
Abstract
In Alzheimer's disease, all ganglio-series gangliosides (GM1, GD1a, GD1b and GT1b) were found to be decreased in temporal and frontal cortex, and nucleus basalis of Meynert. In addition, in Alzheimer's disease simple gangliosides (GM2, GM3) were elevated in frontal and parietal cortex, possibly correlating to accelerated lysosomal degradation of gangliosides and/or astrogliosis occurring during neuronal death.Entities:
Mesh：
Substances：
Year: 1992 PMID： 1304338 DOI： 10.1016/0197-0186(92)90058-y
Source DB: PubMed Journal: Neurochem Int ISSN： 0197-0186 Impact factor: 3.921