| Literature DB >> 1299623 |
G Michel1, L Kemény, R U Peter, A Beetz, C Ried, P Arenberger, T Ruzicka.
Abstract
Normal human keratinocytes show chemotactic behavior towards interleukin-8 (IL-8). Under physiological conditions this cytokine seems to be present in an equilibrium between monomeric and dimeric forms, as indicated by Western blotting data. Radioligand binding studies suggest that keratinocyte chemotaxis is mediated by receptors specific for IL-8 dimers. IL-8 receptor-specific mRNA can be detected in a keratinocyte cell line by polymerase chain reaction.Entities:
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Year: 1992 PMID: 1299623 DOI: 10.1016/0014-5793(92)80677-9
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124