Literature DB >> 12975466

Tracking autoimmune T cells in diabetes.

David V Serreze1, Edward H Leiter.   

Abstract

Insulin-dependent diabetes mellitus is usually caused by the autoimmune destruction of pancreatic beta cells by T cells. Methodologies to track the development, migration, and functional activation of one class of such T cells (CD4 T cells) have been limited. However, it now appears that this limitation has been overcome.

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Year:  2003        PMID： 12975466      PMCID： PMC193678          DOI： 10.1172/JCI19842

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  3 in total

1.  Two mechanisms for the non-MHC-linked resistance to spontaneous autoimmunity.

Authors:  J Verdaguer; A Amrani; B Anderson; D Schmidt; P Santamaria
Journal:  J Immunol       Date:  1999-04-15       Impact factor: 5.422

2.  Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity.

Authors:  Thomas Stratmann; Natalia Martin-Orozco; Valérie Mallet-Designe; Laurent Poirot; Dorian McGavern; Grigoriy Losyev; Cathleen M Dobbs; Michael B A Oldstone; Kenji Yoshida; Hitoshi Kikutani; Diane Mathis; Christophe Benoist; Kathryn Haskins; Luc Teyton
Journal:  J Clin Invest       Date:  2003-09       Impact factor: 14.808

3.  Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes.

Authors:  Sylvie Lesage; Suzanne B Hartley; Srinivas Akkaraju; Judith Wilson; Michelle Townsend; Christopher C Goodnow
Journal:  J Exp Med       Date:  2002-11-04       Impact factor: 14.307
  3 in total

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