Literature DB >> 1297526

[Lethal effect of boron neutron capture reaction on human uveal melanoma cells in culture incubated with borophenylalanine].

R Belkhou1, S Mykita, L Meyer, J Sahel, J C Abbé, H Dreyfus, R Massarelli.   

Abstract

Cell cultures obtained from human uveal tumours have been used as experimental model to study the lethal effect consecutive to the neutron capture reaction on boron incorporated into cells as borophenylalanine. An irradiation with a neutron fluence of 6 x 10(9) n cm-2 reduced the number of viable cells by about 30%.

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Year:  1992        PMID: 1297526

Source DB:  PubMed          Journal:  C R Acad Sci III        ISSN: 0764-4469


  1 in total

1.  Uptake and metabolism of boronophenylalanine in human uveal melanoma cells in culture Relevance to boron neutron capture therapy of cancer cells.

Authors:  R Belkhou; J C Abbé; P Pham; N Jasner; J Sahel; H Dreyfus; M Moutaouakkil; R Massarelli
Journal:  Amino Acids       Date:  1995-06       Impact factor: 3.520

  1 in total

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