Literature DB >> 12974482

Ebola virus: from discovery to vaccine.

Heinz Feldmann1, Steven Jones, Hans-Dieter Klenk, Hans-Joachim Schnittler.   

Abstract

Ebola virus, being highly pathogenic for humans and non-human primates and the subject of former weapons programmes, is now one of the most feared pathogens worldwide. In addition, the lack of pre- and post-exposure interventions makes the development of rapid diagnostics, new antiviral agents and protective vaccines a priority for many nations. Further insight into the ecology, immunology and pathogenesis of Ebola virus will promote the delivery of these urgently required tools.

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Year:  2003        PMID： 12974482     DOI： 10.1038/nri1154

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  116 in total

1.  Development and characterization of rabbit and mouse antibodies against ebolavirus envelope glycoproteins.

Authors:  Wu Ou; Josie Delisle; Krishnamurthy Konduru; Steven Bradfute; Sheli R Radoshitzky; Cary Retterer; Krishna Kota; Sina Bavari; Jens H Kuhn; Peter B Jahrling; Gerardo Kaplan; Carolyn A Wilson
Journal:  J Virol Methods       Date:  2011-04-13       Impact factor: 2.014

2.  Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses.

Authors:  Michael Garbutt; Ryan Liebscher; Victoria Wahl-Jensen; Steven Jones; Peggy Möller; Ralf Wagner; Viktor Volchkov; Hans-Dieter Klenk; Heinz Feldmann; Ute Ströher
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

3.  Viral and host proteins that modulate filovirus budding.

Authors:  Yuliang Liu; Ronald N Harty
Journal:  Future Virol       Date:  2010-07-01       Impact factor: 1.831

4.  Effects of Ebola virus glycoproteins on endothelial cell activation and barrier function.

Authors:  Victoria M Wahl-Jensen; Tatiana A Afanasieva; Jochen Seebach; Ute Ströher; Heinz Feldmann; Hans-Joachim Schnittler
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

Review 5.  Laboratory diagnostic systems for Ebola and Marburg hemorrhagic fevers developed with recombinant proteins.

Authors:  Masayuki Saijo; Masahiro Niikura; Tetsuro Ikegami; Ichiro Kurane; Takeshi Kurata; Shigeru Morikawa
Journal:  Clin Vaccine Immunol       Date:  2006-04

6.  Detection of all known filovirus species by reverse transcription-polymerase chain reaction using a primer set specific for the viral nucleoprotein gene.

Authors:  Hirohito Ogawa; Hiroko Miyamoto; Hideki Ebihara; Kimihito Ito; Shigeru Morikawa; Heinz Feldmann; Ayato Takada
Journal:  J Virol Methods       Date:  2010-11-17       Impact factor: 2.014

7.  Ebola virus matrix protein VP40 uses the COPII transport system for its intracellular transport.

Authors:  Seiya Yamayoshi; Takeshi Noda; Hideki Ebihara; Hideo Goto; Yuko Morikawa; Igor S Lukashevich; Gabriele Neumann; Heinz Feldmann; Yoshihiro Kawaoka
Journal:  Cell Host Microbe       Date:  2008-03-13       Impact factor: 21.023

Review 8.  Evidence-based biosafety: a review of the principles and effectiveness of microbiological containment measures.

Authors:  Tjeerd G Kimman; Eric Smit; Michèl R Klein
Journal:  Clin Microbiol Rev       Date:  2008-07       Impact factor: 26.132

9.  Design and synthesis of an antigenic mimic of the Ebola glycoprotein.

Authors:  Ryan D Rutledge; Brian J Huffman; David E Cliffel; David W Wright
Journal:  J Mater Res       Date:  2008       Impact factor: 3.089

10.  Stimulation of Ebola virus production from persistent infection through activation of the Ras/MAPK pathway.

Authors:  James E Strong; Gary Wong; Shane E Jones; Allen Grolla; Steven Theriault; Gary P Kobinger; Heinz Feldmann
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-03       Impact factor: 11.205
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