Literature DB >> 12973941

Expression of telomerase gene mTR in the testis of SD rats and its significance.

Min Fan1, Xiaochun Chen, Zhewei Ye, Yali Xiong, Fuqing Zeng, Gongcheng Lu.   

Abstract

To study the expression of mTR gene in the testis of SD rats with varied ages and its significance, in situ hybridization (ISH) techniques were applied to detect the expression of telomerase gene mTR mRNA in the testis of SD rats. The expression of mTR was found in testes of different-age male SD rats. There was a positive correlation between the expression of mTR and the location of germ cells (spermatogonia, spermatocyte, spermatid). In Setoli cells, leydig cell and spermatozoa, no telomerase mTR was detectable. Type A spermatogonia expressed the highest level of telomerase mTR mRNA. It was suggested that the expression of mTR gene in the testis of SD rats is of lifetime and coincides with the telomerase activity.

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Year:  2003        PMID： 12973941     DOI： 10.1007/BF02859948

Source DB:  PubMed          Journal:  J Huazhong Univ Sci Technolog Med Sci        ISSN： 1672-0733


  7 in total

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Journal:  Endocrinology       Date:  1997-09       Impact factor: 4.736

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Journal:  Science       Date:  1995-09-01       Impact factor: 47.728

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Journal:  Hum Reprod       Date:  1998-06       Impact factor: 6.918

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Journal:  Science       Date:  1994-04-15       Impact factor: 47.728

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Authors:  S Kondo; Y Tanaka; Y Kondo; M Hitomi; G H Barnett; Y Ishizaka; J Liu; T Haqqi; A Nishiyama; B Villeponteau; J K Cowell; B P Barna
Journal:  FASEB J       Date:  1998-07       Impact factor: 5.191
  7 in total

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