Literature DB >> 12973582

[Pragmatic clinical trials: an option in the construction of health-related evidence].

Evandro da Silva Freire Coutinho1, Gisele Huf, Katia Vergetti Bloch.   

Abstract

The authors present and discuss the potential of pragmatic clinical trials as an alternative to both explanatory trials and observational studies to support the use of therapeutic interventions with good evidence. They argue that this strategy, when properly applied, can be a powerful tool to obtain unbiased measures of effectiveness, with simpler logistics and lower costs than in current clinical trials.

Mesh:

Year:  2003        PMID: 12973582     DOI: 10.1590/s0102-311x2003000400039

Source DB:  PubMed          Journal:  Cad Saude Publica        ISSN: 0102-311X            Impact factor:   1.632


  2 in total

1.  Improving the reporting of pragmatic trials: an extension of the CONSORT statement.

Authors:  Merrick Zwarenstein; Shaun Treweek; Joel J Gagnier; Douglas G Altman; Sean Tunis; Brian Haynes; Andrew D Oxman; David Moher
Journal:  BMJ       Date:  2008-11-11

2.  Assessing new strategies for TB diagnosis in low- and middle-income countries.

Authors:  Afrânio Kritski; Paula I Fujiwara; Maria Armanda Vieira; Antonio Ruffino Netto; Martha Maria Oliveira; Gisele Huf; S Bertel Squire
Journal:  Braz J Infect Dis       Date:  2013-03-05       Impact factor: 3.257

  2 in total

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