Literature DB >> 12973270

Vestibular disease and cognitive dysfunction: no evidence for a causal connection.

Martin Gizzi1, Matthew Zlotnick, Keith Cicerone, Ellen Riley.   

Abstract

OBJECTIVE: To evaluate the contribution of vestibular pathology to cognitive and affective complaints of patients with and without brain trauma.
SETTING: An outpatient balance disorders clinic within a tertiary care neuroscience institute. PARTICIPANTS: 200 patients with dizziness--half with a recent history of brain trauma and half without. MAIN OUTCOME MEASURES: The Dizziness Handicap Inventory, the Beck Depression Inventory, and the Neurobehavioral Symptom Inventory were prospectively administered. Neurological examination and vestibular testing were performed to arrive at a diagnosis for the dizziness. Multiple regression analyses were carried out using vestibular diagnosis, psychiatric diagnosis, and trauma history as predictors of the inventory scores.
RESULTS: Perceived disability was higher in dizzy patients with a history of brain trauma compared with dizzy patients without a history of trauma. A diagnosis of vestibular disease had no influence on perceived disability. Similarly, cognitive complaints were more common in dizzy patients with a history of brain trauma compared to dizzy patients without a history of trauma, but a diagnosis of vestibular disease had no influence on the frequency of cognitive complaints.
CONCLUSIONS: In patients with postconcussive dizziness, cognitive complaints are likely due to neurologic injury or affective disturbance. In dizzy patients without brain trauma, cognitive complaints are likely due to concurrent affective disturbance.

Entities:  

Mesh:

Year:  2003        PMID: 12973270     DOI: 10.1097/00001199-200309000-00002

Source DB:  PubMed          Journal:  J Head Trauma Rehabil        ISSN: 0885-9701            Impact factor:   2.710


  8 in total

1.  Postconcussive Symptoms, PTSD, and Medical Disease Burden in Treatment-Seeking OEF/OIF/OND Veterans.

Authors:  Joah L Williams; Meghan E McDevitt-Murphy; James G Murphy; Ellen M Crouse
Journal:  Mil Med       Date:  2017-03       Impact factor: 1.437

2.  Comorbidities confounding the outcomes of surgery for third window syndrome: Outlier analysis.

Authors:  P Ashley Wackym; Heather T Mackay-Promitas; Shaban Demirel; Gerard J Gianoli; Martin S Gizzi; Dale M Carter; David A Siker
Journal:  Laryngoscope Investig Otolaryngol       Date:  2017-08-22

3.  Modulation of memory by vestibular lesions and galvanic vestibular stimulation.

Authors:  Paul F Smith; Lisa H Geddes; Jean-Ha Baek; Cynthia L Darlington; Yiwen Zheng
Journal:  Front Neurol       Date:  2010-11-17       Impact factor: 4.003

4.  Longitudinal Cognitive and Neurobehavioral Functional Outcomes Before and After Repairing Otic Capsule Dehiscence.

Authors:  P Ashley Wackym; Carey D Balaban; Heather T Mackay; Scott J Wood; Christopher J Lundell; Dale M Carter; David A Siker
Journal:  Otol Neurotol       Date:  2016-01       Impact factor: 2.311

Review 5.  Personality changes in patients with vestibular dysfunction.

Authors:  Paul F Smith; Cynthia L Darlington
Journal:  Front Hum Neurosci       Date:  2013-10-29       Impact factor: 3.169

Review 6.  From ear to uncertainty: vestibular contributions to cognitive function.

Authors:  Paul F Smith; Yiwen Zheng
Journal:  Front Integr Neurosci       Date:  2013-11-26

7.  Does Otovestibular Loss in the Autosomal Dominant Disorder DFNA9 Have an Impact of on Cognition? A Systematic Review.

Authors:  Jonas De Belder; Stijn Matthysen; Annes J Claes; Griet Mertens; Paul Van de Heyning; Vincent Van Rompaey
Journal:  Front Neurosci       Date:  2018-01-09       Impact factor: 4.677

8.  Cognitive processing and body balance in elderly subjects with vestibular dysfunction.

Authors:  Giovanna Cristina dos Santos Caixeta; Flávia Doná; Juliana Maria Gazzola
Journal:  Braz J Otorhinolaryngol       Date:  2012-04
  8 in total

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