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Literature DB >> 12970461

Detection of a gene cluster that is dispensable for human herpesvirus 6 replication and latency.

Kazuhiro Kondo¹, Hideo Nozaki, Kazuya Shimada, Koichi Yamanishi.

Abstract

The U3-U7 gene cluster of human herpesvirus 6 (HHV-6) was replaced with an enhanced green fluorescent protein-puromycin gene cassette containing the cytomegalovirus major immediate-early promoter. Neither viral replication in T cells nor latency and reactivation in macrophages was impaired. During HHV-6 latency, the cytomegalovirus promoter used the transcription start sites employed in cytomegalovirus latency.

Entities: Species

Mesh：

Year: 2003 PMID： 12970461 PMCID： PMC228414 DOI： 10.1128/jvi.77.19.10719-10724.2003

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

35 in total

1. A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.

Authors: V S Goldmacher; L M Bartle; A Skaletskaya; C A Dionne; N L Kedersha; C A Vater; J W Han; R J Lutz; S Watanabe; E D Cahir McFarland; E D Kieff; E S Mocarski; T Chittenden
Journal: Proc Natl Acad Sci U S A Date: 1999-10-26 Impact factor: 11.205

2. Identification of human herpesvirus 6 latency-associated transcripts.

Authors: Kazuhiro Kondo; Kazuya Shimada; Junji Sashihara; Keiko Tanaka-Taya; Koichi Yamanishi
Journal: J Virol Date: 2002-04 Impact factor: 5.103

3. A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation.

Authors: A Skaletskaya; L M Bartle; T Chittenden; A L McCormick; E S Mocarski; V S Goldmacher
Journal: Proc Natl Acad Sci U S A Date: 2001-06-26 Impact factor: 11.205

4. Disruption of mitochondrial networks by the human cytomegalovirus UL37 gene product viral mitochondrion-localized inhibitor of apoptosis.

Authors: A Louise McCormick; Vanessa L Smith; Dar Chow; Edward S Mocarski
Journal: J Virol Date: 2003-01 Impact factor: 5.103

5. Recognition of a novel stage of betaherpesvirus latency in human herpesvirus 6.

Authors: Kazuhiro Kondo; Junji Sashihara; Kazuya Shimada; Masaya Takemoto; Kiyoko Amo; Hiromi Miyagawa; Koichi Yamanishi
Journal: J Virol Date: 2003-02 Impact factor: 5.103

6. Products of US22 genes M140 and M141 confer efficient replication of murine cytomegalovirus in macrophages and spleen.

Authors: L K Hanson; J S Slater; Z Karabekian; G Ciocco-Schmitt; A E Campbell
Journal: J Virol Date: 2001-07 Impact factor: 5.103

7. Promoter-regulatory region of the major immediate early gene of human cytomegalovirus.

Authors: D R Thomsen; R M Stenberg; W F Goins; M F Stinski
Journal: Proc Natl Acad Sci U S A Date: 1984-02 Impact factor: 11.205

Review 8. Human herpesvirus 6.

Authors: M T Caserta; D J Mock; S Dewhurst
Journal: Clin Infect Dis Date: 2001-08-10 Impact factor: 9.079

9. Human herpesvirus 6B genome sequence: coding content and comparison with human herpesvirus 6A.

Authors: G Dominguez; T R Dambaugh; F R Stamey; S Dewhurst; N Inoue; P E Pellett
Journal: J Virol Date: 1999-10 Impact factor: 5.103

10. Characterisation of a human herpesvirus 6 variant A 'amplicon' and replication modulation by U94-Rep 'latency gene'.

Authors: Simon Turner; Dario DiLuca; Ursula Gompels
Journal: J Virol Methods Date: 2002-09 Impact factor: 2.014

5 in total

Review 1. The molecular biology of human herpesvirus-6 latency and telomere integration.

Authors: Jesse H Arbuckle; Peter G Medveczky
Journal: Microbes Infect Date: 2011-03-31 Impact factor: 2.700

2. The DR1 and DR6 first exons of human herpesvirus 6A are not required for virus replication in culture and are deleted in virus stocks that replicate well in T-cell lines.

Authors: Ronen Borenstein; Haim Zeigerman; Niza Frenkel
Journal: J Virol Date: 2010-01-06 Impact factor: 5.103