Literature DB >> 12970460

The gene that encodes the herpes simplex virus type 1 latency-associated transcript influences the accumulation of transcripts (Bcl-x(L) and Bcl-x(S)) that encode apoptotic regulatory proteins.

Weiping Peng1, Gail Henderson, Guey-Chuen Perng, Anthony B Nesburn, Steven L Wechsler, Clinton Jones.   

Abstract

The herpes simplex virus type 1 latency-associated transcript (LAT) inhibits apoptosis. We demonstrate here that LAT influences the accumulation of the Bcl-x(L) transcript versus the Bcl-x(S) transcript in Neuro-2A cells. Bcl-x(L) encodes an antiapoptotic protein, whereas Bcl-x(S) encodes a proapoptotic protein. Promoting the accumulation of Bcl-x(L) in neurons may inhibit apoptosis, thus enhancing the latency-reactivation cycle.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12970460      PMCID： PMC228484          DOI： 10.1128/jvi.77.19.10714-10718.2003

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  48 in total

Review 1.  FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis.

Authors:  A Krueger; S Baumann; P H Krammer; S Kirchhoff
Journal:  Mol Cell Biol       Date:  2001-12       Impact factor: 4.272

2.  Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo.

Authors:  Maryam Ahmed; Martin Lock; Cathie G Miller; Nigel W Fraser
Journal:  J Virol       Date:  2002-01       Impact factor: 5.103

3.  Herpes simplex virus type 1 2-kilobase latency-associated transcript intron associates with ribosomal proteins and splicing factors.

Authors:  M Ahmed; N W Fraser
Journal:  J Virol       Date:  2001-12       Impact factor: 5.103

4.  Dynamics of expression of apoptosis-regulatory proteins Bid, Bcl-2, Bcl-X, Bax and Bak during development of murine nervous system.

Authors:  M Krajewska; J K Mai; J M Zapata; K W S Ashwell; S L Schendel; J C Reed; S Krajewski
Journal:  Cell Death Differ       Date:  2002-02       Impact factor: 15.828

5.  Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein.

Authors:  Alexander H Stegh; Bryan C Barnhart; Jorg Volkland; Alicia Algeciras-Schimnich; Ning Ke; John C Reed; Marcus E Peter
Journal:  J Biol Chem       Date:  2001-12-03       Impact factor: 5.157

6.  HSV and glycoprotein J inhibit caspase activation and apoptosis induced by granzyme B or Fas.

Authors:  K R Jerome; Z Chen; R Lang; M R Torres; J Hofmeister; S Smith; R Fox; C J Froelich; L Corey
Journal:  J Immunol       Date:  2001-10-01       Impact factor: 5.422

7.  A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 latency-associated transcript gene and restore wild-type reactivation levels.

Authors:  Guey-Chuen Perng; Barak Maguen; Ling Jin; Kevin R Mott; Nelson Osorio; Susan M Slanina; Ada Yukht; Homayon Ghiasi; Anthony B Nesburn; Melissa Inman; Gail Henderson; Clinton Jones; Steven L Wechsler
Journal:  J Virol       Date:  2002-02       Impact factor: 5.103

Review 8.  Modulation of apoptosis during herpes simplex virus infection in human cells.

Authors:  M Aubert; J A Blaho
Journal:  Microbes Infect       Date:  2001-08       Impact factor: 2.700

9.  Herpesvirus hominis: isolation from human trigeminal ganglion.

Authors:  F O Bastian; A S Rabson; C L Yee; T S Tralka
Journal:  Science       Date:  1972-10-20       Impact factor: 47.728

10.  Regulation of caspase 8- and caspase 9-induced apoptosis by the herpes simplex virus type 1 latency-associated transcript.

Authors:  Gail Henderson; Weiping Peng; Ling Jin; Guey-Chuen Perng; Anthony B Nesburn; Steven L Wechsler; Clinton Jones
Journal:  J Neurovirol       Date:  2002-12       Impact factor: 2.643
View more
  13 in total

1.  Identification of herpes simplex virus type 1 proteins encoded within the first 1.5 kb of the latency-associated transcript.

Authors:  Gail Henderson; Tareq Jaber; Dale Carpenter; Steven L Wechsler; Clinton Jones
Journal:  J Neurovirol       Date:  2009-09       Impact factor: 2.643

2.  The herpes simplex virus type 1 locus that encodes the latency-associated transcript enhances the frequency of encephalitis in male BALB/c mice.

Authors:  Clinton Jones; Melissa Inman; Weiping Peng; Gail Henderson; Alan Doster; Guey-Chuen Perng; Anisa Kaenjak Angeletti
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

3.  A protein encoded by the bovine herpesvirus 1 latency-related gene interacts with specific cellular regulatory proteins, including CCAAT enhancer binding protein alpha.

Authors:  Florencia Meyer; Sandra Perez; Vicki Geiser; Mark Sintek; Melissa Inman; Clinton Jones
Journal:  J Virol       Date:  2006-09-20       Impact factor: 5.103

4.  A herpes simplex virus type 1 mutant expressing a baculovirus inhibitor of apoptosis gene in place of latency-associated transcript has a wild-type reactivation phenotype in the mouse.

Authors:  Ling Jin; Guey-Chuen Perng; Kevin R Mott; Nelson Osorio; Julia Naito; David J Brick; Dale Carpenter; Clinton Jones; Steven L Wechsler
Journal:  J Virol       Date:  2005-10       Impact factor: 5.103

5.  The locus encompassing the latency-associated transcript of herpes simplex virus type 1 interferes with and delays interferon expression in productively infected neuroblastoma cells and trigeminal Ganglia of acutely infected mice.

Authors:  Weiping Peng; Gail Henderson; Melissa Inman; Lbachir BenMohamed; Guey-Chuen Perng; Steven L Wechsler; Clinton Jones
Journal:  J Virol       Date:  2005-05       Impact factor: 5.103

6.  Herpes simplex virus type 1 latency-associated transcript inhibits apoptosis and promotes neurite sprouting in neuroblastoma cells following serum starvation by maintaining protein kinase B (AKT) levels.

Authors:  Sumin Li; Dale Carpenter; Chinhui Hsiang; Steven L Wechsler; Clinton Jones
Journal:  J Gen Virol       Date:  2009-12-02       Impact factor: 3.891

7.  Identification of a novel herpes simplex virus type 1 transcript and protein (AL3) expressed during latency.

Authors:  Tareq Jaber; Gail Henderson; Sumin Li; Guey-Chuen Perng; Dale Carpenter; Steven L Wechsler; Clinton Jones
Journal:  J Gen Virol       Date:  2009-07-01       Impact factor: 3.891

8.  Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia.

Authors:  Minfeng Shu; Te Du; Grace Zhou; Bernard Roizman
Journal:  Proc Natl Acad Sci U S A       Date:  2015-08-24       Impact factor: 11.205

9.  Two small RNAs encoded within the first 1.5 kilobases of the herpes simplex virus type 1 latency-associated transcript can inhibit productive infection and cooperate to inhibit apoptosis.

Authors:  Wenwen Shen; Mariana Sa e Silva; Tareq Jaber; Olga Vitvitskaia; Sumin Li; Gail Henderson; Clinton Jones
Journal:  J Virol       Date:  2009-07-08       Impact factor: 5.103

10.  Identification of two small RNAs within the first 1.5-kb of the herpes simplex virus type 1-encoded latency-associated transcript.

Authors:  Weiping Peng; Olga Vitvitskaia; Dale Carpenter; Steven L Wechsler; Clinton Jones
Journal:  J Neurovirol       Date:  2008-01       Impact factor: 2.643
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.