| Literature DB >> 12967724 |
J G Pilitsis1, W M Coplin, M H O'Regan, J M Wellwood, F G Diaz, M R Fairfax, D B Michael, J W Phillis.
Abstract
Free fatty acid (FFA) concentrations in cerebrospinal fluid (CSF) from patients with ischemic and hemorrhagic stroke (n=25) and in contemporary controls (n=73) were examined using HPLC. Concentrations of CSF FFAs from ischemic and hemorrhagic stroke patients obtained within 48 h of the insult were significantly greater than in control patients. Higher concentrations of polyunsaturated fatty acids (PUFAs) in CSF obtained within 48 h of insult were associated with significantly lower (P<0.05) admission Glasgow Coma Scale scores and worse outcome at the time of hospital discharge, using the Glasgow Outcome Scale (P<0.01).Entities:
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Year: 2003 PMID： 12967724 DOI： 10.1016/s0006-8993(03)03044-0
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252