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Literature DB >> 12966

Interaction of DNA with DNA-binding proteins. The characterization of protein HD from Escherichia coli and its nucleic acid complexes.

Abstract

DNA-binding protein HD with a monomer molecular weight of 9000 was isolated from Escherichia coli cells. The protein occurs as a tetramer under native conditions and binds to single and double-stranded DNA and also to RNA. DNA complexed with protein HD is a poor template for DNA synthesis by E. coli polymerase I, II or III holoenzyme. Exonuclease III is hindered in degrading HD-protein-covered double-stranded DNA, whereas exonuclease I can digest complexed single-stranded DNA. Transcription is liqhtly stimulated in the presence of protein HD.

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Year: 1976 PMID： 12966 DOI： 10.1111/j.1432-1033.1976.tb11132.x

Source DB: PubMed Journal: Eur J Biochem ISSN： 0014-2956

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Cited

19 in total

1. Preferential binding of E.coli histone-like protein HU alpha to negatively supercoiled DNA.

Authors: H Shindo; A Furubayashi; M Shimizu; M Miyake; F Imamoto
Journal: Nucleic Acids Res Date: 1992-04-11 Impact factor: 16.971

2. An RNA transcribed from DNA at the origin of phage fd single strand to replicative form conversion.

Authors: K Geider; E Beck; H Schaller
Journal: Proc Natl Acad Sci U S A Date: 1978-02 Impact factor: 11.205

Review 3. Histonelike proteins of bacteria.

Authors: K Drlica; J Rouviere-Yaniv
Journal: Microbiol Rev Date: 1987-09

Interaction of DNA with DNA-binding proteins. The characterization of protein HD from Escherichia coli and its nucleic acid complexes.

1. Preferential binding of E.coli histone-like protein HU alpha to negatively supercoiled DNA.

2. An RNA transcribed from DNA at the origin of phage fd single strand to replicative form conversion.

Review 3. Histonelike proteins of bacteria.

4. Intracellular location of the histonelike protein HU in Escherichia coli.

5. A bacterial protein requirement for the bacteriophage lambda terminase reaction.

6. Host cell metabolic energy is not required for injection of bacteriophage T5 DNA.

7. HU histone-like DNA-binding protein from Thermus thermophilus: structural and evolutionary analyses.

8. Protein HU in the enzymatic replication of the chromosomal origin of Escherichia coli.

9. Prokaryotic histone-like protein interacting with RNA polymerase.

10. Novel histone H2A-like protein of escherichia coli.