Literature DB >> 12965297

The contribution of signaling pathways to olfactory organization and development.

Randall R Reed1.   

Abstract

The exquisite specificity in the organization of the mammalian olfactory system underlies its remarkable sensitivity and precision in odorant detection. The contribution of olfactory receptor proteins to the initial patterning of connections between the sensory epithelium and the bulb is widely appreciated. The application of genetic model systems has revealed additional roles for odorant-evoked activity in the development, organization and dynamic turnover of cells in this regenerating sensory organ.

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Year:  2003        PMID: 12965297     DOI: 10.1016/s0959-4388(03)00104-1

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN: 0959-4388            Impact factor:   6.627


  2 in total

1.  Odorant-induced activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in the olfactory bulb promotes survival of newly formed granule cells.

Authors:  Naofumi Miwa; Daniel R Storm
Journal:  J Neurosci       Date:  2005-06-01       Impact factor: 6.167

2.  Odorant receptors at the growth cone are coupled to localized cAMP and Ca2+ increases.

Authors:  Micol Maritan; Giovanni Monaco; Ilaria Zamparo; Manuela Zaccolo; Tullio Pozzan; Claudia Lodovichi
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-13       Impact factor: 11.205

  2 in total

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