Literature DB >> 12964071

[Non-occlusive mesenteric ischemia].

S C Krämer1, J Görich, F Oertel, H Scheld, W Heindel.   

Abstract

The so-called non-occlusive disease (NOD) or non-occlusive mesenteric ischemia (NOMI) is a severe and life-threatening pathology. Even under optimal circumstances and standardised diagnostic and therapeutic procedures maximum survival rates do not exceed 50 %. The NOD is a pathology of the elder patient and its incidence rises with other comorbidities such as reduced cardiac output, diabetes and renal insufficiency. Induction of the disease with a severe vasoconstriction of the splanchnic vessels may be a simple cardiac decompensation, a frequent trigger however is a previous heart surgery with consecutive cardiac shock. Early diagnosis is difficult to conduct because of unspecific symptoms. Beside abdominal pain in awake patients, ileus or subileus is remaining the single acute symptom which could be also a consequence of a postoperative paralysis. Laboratory parameters such as leucocytosis and elevated lactat levels are often positive, but unspecific and the latter may be a delayed sign of progressive disease. The only sufficient method for diagnosis implicating a possible treatment option seems to be an immediate angiographic examination. Because of the disappointing results of a solitary surgical approach transarterial medication via catheter is indicated. Depending of the course of the disease only a combination of local mesenteric infusion of vasodilatory drugs and surgical resection of already necrotic bowel promises a successful therapeutic approach and better survival rates.

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Year:  2003        PMID: 12964071     DOI: 10.1055/s-2003-41923

Source DB:  PubMed          Journal:  Rofo        ISSN: 1438-9010


  6 in total

1.  [Targeted diagnosis of mesenteric ischemia].

Authors:  Sven Winkler; Lars Kamper; Stefanie Jansen; Nadine Abanador-Kamper; Werner Piroth; Patrick Haage
Journal:  Med Klin (Munich)       Date:  2009-12-15

2.  Sickle cell diseases and ileus.

Authors:  Mehmet Rami Helvaci; Akin Aydogan; Seckin Akkucuk; Cem Oruc; Mustafa Ugur
Journal:  Int J Clin Exp Med       Date:  2014-09-15

3.  A Wolf in Sheep's Clothing: A Case of Dilated Cardiomyopathy Presenting with Nonspecific Digestive Symptoms: Insights into Nonocclusive Mesenteric Ischemia.

Authors:  Antoine Kossaify
Journal:  Case Rep Med       Date:  2011-10-25

4.  Outcome after surgery for acute right-sided colonic ischemia without feasible vascular intervention: a single center experience of 58 patients over 6 years.

Authors:  Samuel A Käser; Tara C Müller; Anna Guggemos; Ulrich Nitsche; Christoph Späth; Christoph A Maurer; Klaus-Peter Janssen; Jörg Kleeff; Helmut Friess; Dirk Wilhelm; Franz G Bader
Journal:  BMC Surg       Date:  2015-03-21       Impact factor: 2.102

5.  The role of multislice computed tomography (MSCT) angiography in the diagnosis and therapy of non-occlusive mesenteric ischemia (NOMI): Could MSCT replace DSA in diagnosis?

Authors:  Sara Kammerer; Christoph Schuelke; Shoma Berkemeyer; Aglae Velasco; Walter Heindel; Michael Koehler; Boris Buerke
Journal:  PLoS One       Date:  2018-03-01       Impact factor: 3.240

6.  Predictors of response to intra-arterial vasodilatory therapy of non-occlusive mesenteric ischemia in patients with severe shock: results from a prospective observational study.

Authors:  Nina Rittgerodt; Thorben Pape; Sascha David; Klaus Stahl; Markus Busch; Lena S Becker; Andrea Schneider; Heiner Wedemeyer; Benjamin Seeliger; Julius Schmidt; Anna Maria Hunkemöller; Jan Fuge; Wolfgang Knitsch; Christine Fegbeutel; Hans-Jörg Gillmann; Bernhard C Meyer; Marius M Hoeper; Jan B Hinrichs
Journal:  Crit Care       Date:  2022-04-04       Impact factor: 9.097

  6 in total

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