Literature DB >> 12963836

A new role for E2F-1 in checkpoint control.

Craig Stevens1, Nicholas B La Thangue.   

Abstract

In response to DNA damage, E2F-1 is induced and phosphorylated. Phosphorylated E2F-1 can reside in discrete nuclear structures and induce apoptosis, suggesting a unique role for E2F-1 in DNA repair and checkpoint functions.

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Year:  2003        PMID： 12963836

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  8 in total

1.  Atypical E2F activity coordinates PHR1 photolyase gene transcription with endoreduplication onset.

Authors:  Amandine Radziejwoski; Kobe Vlieghe; Tim Lammens; Barbara Berckmans; Sara Maes; Marcel A K Jansen; Claudia Knappe; Andreas Albert; Harald K Seidlitz; Günther Bahnweg; Dirk Inzé; Lieven De Veylder
Journal:  EMBO J       Date:  2010-12-03       Impact factor: 11.598

2.  A novel E2F-like protein involved in transcriptional activation of cyst wall protein genes in Giardia lamblia.

Authors:  Li-Hsin Su; Yu-Jiao Pan; Yu-Chang Huang; Chao-Cheng Cho; Chia-Wei Chen; Shao-Wei Huang; Sheng-Fung Chuang; Chin-Hung Sun
Journal:  J Biol Chem       Date:  2011-08-11       Impact factor: 5.157

3.  Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control.

Authors:  Christopher A Reed; Christopher N Mayhew; A Kathleen McClendon; Erik S Knudsen
Journal:  J Biol Chem       Date:  2009-11-02       Impact factor: 5.157

4.  Ebola virus-like particle-induced activation of NF-kappaB and Erk signaling in human dendritic cells requires the glycoprotein mucin domain.

Authors:  Osvaldo Martinez; Charalampos Valmas; Christopher F Basler
Journal:  Virology       Date:  2007-04-16       Impact factor: 3.616

5.  RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1.

Authors:  C A Reed; C N Mayhew; A K McClendon; X Yang; A Witkiewicz; E S Knudsen
Journal:  Oncogene       Date:  2009-10-19       Impact factor: 9.867

Review 6.  Atypical E2Fs: new players in the E2F transcription factor family.

Authors:  Tim Lammens; Jing Li; Gustavo Leone; Lieven De Veylder
Journal:  Trends Cell Biol       Date:  2009-02-07       Impact factor: 20.808

Review 7.  E2F8 is a Potential Therapeutic Target for Hepatocellular Carcinoma.

Authors:  Yi Lv; Jia Xiao; Jing Liu; Feiyue Xing
Journal:  J Cancer       Date:  2017-04-09       Impact factor: 4.207

8.  KMT Set7/9 affects genotoxic stress response via the Mdm2 axis.

Authors:  Larissa Lezina; Vasilisa Aksenova; Olga Fedorova; Daria Malikova; Oleg Shuvalov; Alexey V Antonov; Dmitri Tentler; Alexander V Garabadgiu; Gerry Melino; Nikolai A Barlev
Journal:  Oncotarget       Date:  2015-09-22
  8 in total

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