Literature DB >> 12959423

Lower cortisol and higher ACTH levels in individuals with autism.

Jasna Marinović Curin1, Janos Terzić, Zorana Bujas Petković, Ljubinka Zekan, Ivana Marinović Terzić, Ivana Marasović Susnjara.   

Abstract

Blood concentrations of pituitary hormones adrenocorticotropin (ACTH), prolactin, growth hormone, and adrenal hormone-cortisol were measured in 36 autistic and 27 control individuals. Individuals with autism had significantly lower serum concentrations of cortisol (p < 10(-6)), and significantly higher concentrations of ACTH (p = 0.002) than control age- and sex-matched subjects. Also, prolactin concentrations in autistic patients with epilepsy were significantly higher when compared with normal subjects. The observed hormonal changes may indicate dysfunction of the hypothalamo-pituitary-adrenal axis in individuals with autism.

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Year:  2003        PMID： 12959423     DOI： 10.1023/a:1025019030121

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN： 0162-3257


  32 in total

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  37 in total

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6.  Slower cortisol response during ACTH stimulation test in autistic children.

Authors:  Jasna Marinović-Curin; Ivana Marinović-Terzić; Zorana Bujas-Petković; Ljubinka Zekan; Veselin Skrabić; Zoran Dogas; Janos Terzić
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9.  Basal and adrenocorticotropic hormone stimulated plasma cortisol levels among Egyptian autistic children: relation to disease severity.

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10.  Corticosterone Signaling and a Lateral Habenula-Ventral Tegmental Area Circuit Modulate Compulsive Self-Injurious Behavior in a Rat Model.

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