Literature DB >> 12954711

Transient lupus anticoagulant: an unusual cause of bruising in children.

A K Anderson1, U Mohan, R Liesner.   

Abstract

A child presented with excessive bruising and prolonged activated partial thromboplastin time. Mixing studies in plasma were positive for phospholipid dependence of the anticoagulant, confirming a diagnosis of lupus anticoagulant. Factor II level was reduced. Laboratory findings normalised after three months, with spontaneous resolution of bruising. This case demonstrates a transient antiphospholipid antibody syndrome as a rare presentation of bleeding diathesis in a previously healthy child, and should be considered in children with new onset bruising and prolonged activated partial thromboplastin time.

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Year:  2003        PMID: 12954711      PMCID: PMC1726190          DOI: 10.1136/emj.20.5.e6

Source DB:  PubMed          Journal:  Emerg Med J        ISSN: 1472-0205            Impact factor:   2.740


  1 in total

Review 1.  Lupus anticoagulant-hypoprothrombinemia syndrome and immunoglobulin-A vasculitis: a report of Japanese sibling cases and review of the literature.

Authors:  Kaori Fujiwara; Junya Shimizu; Hirokazu Tsukahara; Akira Shimada
Journal:  Rheumatol Int       Date:  2019-08-07       Impact factor: 2.631

  1 in total

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