| Literature DB >> 12954074 |
Wolfgang Eisenreich1, Ernst Kupfer, Peter Stohler, Wolfgang Weber, Adelbert Bacher.
Abstract
The lipophilic beta-lactone, lipstatin, inhibits pancreatic lipase and has been shown earlier to be biosynthesized by Claisen condensation of two fatty acid moieties. We present data from incorporation experiments with [U-13C6]leucine showing that a branched chain analogue of lipstatin is biosynthesized from leucine.Entities:
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Year: 2003 PMID： 12954074 DOI： 10.1021/jm030780x
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446