Literature DB >> 12951097

Synthesis of methyl (5S,6R,7E,9E,11Z,13E,15S)-16-(4-fluorophenoxy)-5,6,15-trihydroxy-7,9,11,13-hexadecatetraenoate, an analogue of 15R-lipoxin A4.

Eifion D Phillips1, Hui-Fang Chang, Christopher R Holmquist, John P McCauley.   

Abstract

We describe a method for the synthesis of methyl (5S,6R,7E,9E,11Z,13E,15S)-16-(4-fluorophenoxy)-5,6,15-trihydroxy-7,9,11,13-hexadecatetraenoate, a compound that has been described as a metabolically stable analogue of 15R-lipoxin A(4).

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Year:  2003        PMID: 12951097     DOI: 10.1016/s0960-894x(03)00667-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Expeditious Enyne Construction from Alkynes via Oxidative Pd(II) Catalyzed Heck-Type Coupling.

Authors:  Victor Hadi; Kyung Soo Yoo; Min Jeong; Kyung Woon Jung
Journal:  Tetrahedron Lett       Date:  2009-05-20       Impact factor: 2.415

2.  Synthesis of aromatic lactone analogues of Lipoxin A4.

Authors:  Aya Ismael; Muhammad Zeeshan; Jørn H Hansen
Journal:  BMC Res Notes       Date:  2022-02-09
  2 in total

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