| Literature DB >> 12951086 |
Mirjana Popsavin1, Ljilja Torović, Vesna Kojić, Gordana Bogdanović, Sasa Spaić, Velimir Popsavin.
Abstract
A divergent synthesis of two novel tiazofurin analogues, 2-(3-deoxy-3-fluoro-beta-D-xylofuranosyl)thiazole-4-carboxamide (2) and 2-(3-acetamido-3-deoxy-beta-D-xylofuranosyl)thiazole-4-carboxamide (3), has been achieved starting from D-glucose. Both nucleoside analogues were evaluated for their in vitro cytotoxicity against several human leukaemia and solid tumour cell lines.Entities:
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Year: 2003 PMID： 12951086 DOI： 10.1016/s0960-894x(03)00712-1
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823