Literature DB >> 12951081

Synthesis of S6-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its incorporation into oligoribonucleotides.

Qinguo Zheng1, Yang Wang, Eric Lattmann.   

Abstract

The preparation of N(2)-phenoxylacetyl-S(6)-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its subsequent incorporation into oligoribonucleotides is described. The identity of the oligonucleotides was confirmed by UV spectrophotometry and nucleoside composition analysis.

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Year:  2003        PMID： 12951081     DOI： 10.1016/s0960-894x(03)00716-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells.

Authors:  Christelle Moreau; Tanja Kirchberger; Bo Zhang; Mark P Thomas; Karin Weber; Andreas H Guse; Barry V L Potter
Journal:  J Med Chem       Date:  2012-02-08       Impact factor: 7.446

2.  Thermodynamic and structural contributions of the 6-thioguanosine residue to helical properties of RNA.

Authors:  Michał Gładysz; Witold Andrałojć; Tomasz Czapik; Zofia Gdaniec; Ryszard Kierzek
Journal:  Sci Rep       Date:  2019-03-13       Impact factor: 4.379
  2 in total

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