| Literature DB >> 12951078 |
Zhonghua Pei1, Xiaofeng Li, Gang Liu, Cele Abad-Zapatero, Tom Lubben, Tianyuan Zhang, Stephen J Ballaron, Charles W Hutchins, James M Trevillyan, Michael R Jirousek.
Abstract
A salicylate second site binder was linked to three classes of phosphotyrosine mimetics to produce potent protein tyrosine phosphatase 1B (PTP1B) inhibitors which exhibit significant selectivity against other phosphatases including the most homologous member, TCPTP.Entities:
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Year: 2003 PMID： 12951078 DOI： 10.1016/s0960-894x(03)00725-x
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823