| Literature DB >> 12950673 |
H Kohler1, J Bayry, A Nicoletti, S V Kaveri.
Abstract
Natural autoantibodies (NAbs), produced by B-1 B-cells, are directed against autoantigens and pathogens. NAbs can capture and present antigen to T helper cells thereby initiating adaptive immunities. It is proposed that screening for NAbs against pathogens will predict the strength of an antigen-induced immune response and could be used as a tool for vaccine development.Entities:
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Year: 2003 PMID: 12950673 DOI: 10.1046/j.1365-3083.2003.01314.x
Source DB: PubMed Journal: Scand J Immunol ISSN: 0300-9475 Impact factor: 3.487