Literature DB >> 12947746

[Tularemia, a potential bioterrorism weapon].

Philippe Bossi1, François Bricaire.   

Abstract

A POTENTIAL WEAPON: Because of its highly contagious nature with a low inoculum, principally with the biovar A, F. tularensis is considered as an agent that could be used by terrorists, notably when sprayed. Any epidemic of tularemia, essentially in its respiratory form, particularly in areas of low incidence of this infection, should be suspected to be a biowarfare attack. The voluntary contamination of water with this bacteria could also be used as a biological weapon. THE DIFFERENT FORMS OF THE DISEASE: Depend on the mode of contamination, the dose of inoculum and the virulence of the strains. The forms are pulmonary, ulcerous-glandular, typhoid, glandular, ocular-glandular, oropharyngeal and septicemic. IN GENERAL PRACTICE: Tularemia is a disease that requires official notification. Many guidelines exist for the treatment and prophylaxis of patients having been exposed to F. tularensis.

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Year:  2003        PMID: 12947746

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  7 in total

1.  EmrA1 membrane fusion protein of Francisella tularensis LVS is required for resistance to oxidative stress, intramacrophage survival and virulence in mice.

Authors:  Zhuo Ma; Sukalyani Banik; Harshita Rane; Vanessa T Mora; Seham M Rabadi; Christopher R Doyle; David G Thanassi; Chandra Shekhar Bakshi; Meenakshi Malik
Journal:  Mol Microbiol       Date:  2014-02-08       Impact factor: 3.501

2.  Repression of inflammasome by Francisella tularensis during early stages of infection.

Authors:  Rachel J Dotson; Seham M Rabadi; Elizabeth L Westcott; Stephen Bradley; Sally V Catlett; Sukalyani Banik; Jonathan A Harton; Chandra Shekhar Bakshi; Meenakshi Malik
Journal:  J Biol Chem       Date:  2013-07-02       Impact factor: 5.157

3.  Characterization of a Unique Outer Membrane Protein Required for Oxidative Stress Resistance and Virulence of Francisella tularensis.

Authors:  Maha Alqahtani; Zhuo Ma; Harshada Ketkar; Ragavan Varadharajan Suresh; Meenakshi Malik; Chandra Shekhar Bakshi
Journal:  J Bacteriol       Date:  2018-03-26       Impact factor: 3.490

4.  Contribution of citrulline ureidase to Francisella tularensis strain Schu S4 pathogenesis.

Authors:  Manish Mahawar; Girish S Kirimanjeswara; Dennis W Metzger; Chandra Shekhar Bakshi
Journal:  J Bacteriol       Date:  2009-06-05       Impact factor: 3.490

5.  Development of a Multivalent Subunit Vaccine against Tularemia Using Tobacco Mosaic Virus (TMV) Based Delivery System.

Authors:  Sukalyani Banik; Ahd Ahmed Mansour; Ragavan Varadharajan Suresh; Sherri Wykoff-Clary; Meenakshi Malik; Alison A McCormick; Chandra Shekhar Bakshi
Journal:  PLoS One       Date:  2015-06-22       Impact factor: 3.240

6.  An Improved Tobacco Mosaic Virus (TMV)-Conjugated Multiantigen Subunit Vaccine Against Respiratory Tularemia.

Authors:  Ahd A Mansour; Sukalyani Banik; Ragavan V Suresh; Hardeep Kaur; Meenakshi Malik; Alison A McCormick; Chandra S Bakshi
Journal:  Front Microbiol       Date:  2018-06-05       Impact factor: 5.640

7.  Identification of a live attenuated vaccine candidate for tularemia prophylaxis.

Authors:  Manish Mahawar; Seham M Rabadi; Sukalyani Banik; Sally V Catlett; Dennis W Metzger; Meenakshi Malik; Chandra Shekhar Bakshi
Journal:  PLoS One       Date:  2013-04-17       Impact factor: 3.240

  7 in total

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