Literature DB >> 12945941

Cannabis use as described by people with multiple sclerosis.

S A Page1, M J Verhoef, R A Stebbins, L M Metz, J C Levy.   

Abstract

BACKGROUND: Multiple sclerosis (MS) is one of the most common neurological diseases affecting young adults. The prevalence of MS in Alberta has been described as among the highest reported in the world, estimated at 217 per 100,000. Numerous anecdotal reports, and a few small empirical investigations have suggested that cannabis use may relieve the symptom experience of those with MS. The present study was undertaken to describe cannabis use by this patient group. Information on peoples' beliefs, practices and experiences related to use were investigated.
METHODS: A questionnaire was mailed to a sample of 780 adults with MS in southern Alberta, Canada.
RESULTS: Completed questionnaires were returned by 420/673 eligible subjects (response rate 62%). Mean sample age was 48 years and 75% were women. Respondents ranged from mildly to severely impaired. The majority of respondents (96%) was aware cannabis was potentially therapeutically useful for MS and most (72%) supported legalization for medicinal purposes. Forty-three percent had tried cannabis at some point in their lives, 16% for medicinal purposes. Symptoms reported to be ameliorated included anxiety/depression, spasticity and chronic pain. Reasons given for not trying cannabis were the fact that it is an illegal substance, concern about side effects and lack of knowledge on how to obtain it.
CONCLUSIONS: Subjective improvements in symptom experience were reported by the majority of people with MS who currently use cannabis. Further evaluation of this substance is warranted.

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Year:  2003        PMID: 12945941     DOI: 10.1017/s0317167100002584

Source DB:  PubMed          Journal:  Can J Neurol Sci        ISSN: 0317-1671            Impact factor:   2.104


  15 in total

Review 1.  The pharmacotherapy of chronic pain: a review.

Authors:  Mary E Lynch; C Peter N Watson
Journal:  Pain Res Manag       Date:  2006       Impact factor: 3.037

2.  Medicinal marijuana use: experiences of people with multiple sclerosis.

Authors:  Stacey A Page; Marja J Verhoef
Journal:  Can Fam Physician       Date:  2006-01       Impact factor: 3.275

Review 3.  Role of cannabinoids in multiple sclerosis.

Authors:  John P Zajicek; Vicentiu I Apostu
Journal:  CNS Drugs       Date:  2011-03       Impact factor: 5.749

4.  Marijuana Use by Patients with Multiple Sclerosis.

Authors:  Sheila Gupta; Kelly Fellows; Bianca Weinstock-Guttman; Jesper Hagemeier; Robert Zivadinov; Murali Ramanathan
Journal:  Int J MS Care       Date:  2019 Mar-Apr

5.  The prevalence and incidence of medicinal cannabis on prescription in The Netherlands.

Authors:  Arno Hazekamp; Eibert R Heerdink
Journal:  Eur J Clin Pharmacol       Date:  2013-04-16       Impact factor: 2.953

Review 6.  Cannabinoid-based medicines for neurological disorders--clinical evidence.

Authors:  Stephen Wright
Journal:  Mol Neurobiol       Date:  2007-06-29       Impact factor: 5.590

Review 7.  Cannabinoids and multiple sclerosis.

Authors:  Roger G Pertwee
Journal:  Mol Neurobiol       Date:  2007-06-26       Impact factor: 5.590

8.  Marijuana use patterns among patients with inflammatory bowel disease.

Authors:  Jessica Ravikoff Allegretti; Andrew Courtwright; Matthew Lucci; Joshua R Korzenik; Jonathan Levine
Journal:  Inflamm Bowel Dis       Date:  2013-12       Impact factor: 5.325

9.  Cannabinoid Receptors and Ligands: Lessons from CNS Disorders and the Quest for Novel Treatment Venues.

Authors:  Clara M Vecchini Rodríguez; Yma Escalona Meléndez; Jacqueline Flores-Otero
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

10.  Harm reduction--the cannabis paradox.

Authors:  Robert Melamede
Journal:  Harm Reduct J       Date:  2005-09-22
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