Literature DB >> 12945763

Strategies and methods for the attachment of amino acids and peptides to chiral [n]polynorbornane templates.

Frederick M Pfeffer1, Richard A Russell.   

Abstract

A versatile synthesis of amino acid and peptide functionalised [n]polynorbornane scaffolds is described. The frameworks are constructed using the stereoselective and regioselective cycloaddition of suitably functionalised chiral cyclobutene epoxides with similar norbornenes. The strategies employed allow a range of topologies to be accessed and a number of regioselectively addressable linkage points to be accommodated.

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Year:  2003        PMID： 12945763     DOI： 10.1039/b301980b

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Synthesis of bis-peptides attached on poly[n]norbornene molecular scaffolds with well-defined relative positions and distances.

Authors:  Muhong Shang; Ronald N Warrener; Douglas N Butler; Yasujiro Murata; Davor Margetić
Journal:  Mol Divers       Date:  2010-09-21       Impact factor: 2.943

2.  Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.

Authors:  Matteo Incerti; Massimiliano Tognolini; Simonetta Russo; Daniele Pala; Carmine Giorgio; Iftiin Hassan-Mohamed; Roberta Noberini; Elena B Pasquale; Paola Vicini; Silvia Piersanti; Silvia Rivara; Elisabetta Barocelli; Marco Mor; Alessio Lodola
Journal:  J Med Chem       Date:  2013-03-22       Impact factor: 7.446

Review 3.  Chemistry of a novel zerovalent ruthenium π-acidic alkene complex, Ru (η (6)-1,3,5-cyclooctatriene)(η (2)-dimethyl fumarate)2.

Authors:  Take-Aki Mitsudo; Yasuyuki Ura; Teruyuki Kondo
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2007-05       Impact factor: 3.493
  3 in total

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