Literature DB >> 12945758

A pincer auxiliary to force difficult lactamisations.

Hans Bieräugel1, Hans E Schoemaker, Henk Hiemstra, Jan H van Maarseveen.   

Abstract

A new method to cyclise peptides is reported based on insertion of a salicylaldehyde derived pincer auxiliary in the linear precursor sequence. H-betaAla-Phe-OH and H-Phe-betaAla-OH were chosen as representative model peptides.

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Year:  2003        PMID: 12945758     DOI: 10.1039/b303836j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

Review 1.  Contemporary strategies for peptide macrocyclization.

Authors:  Christopher J White; Andrei K Yudin
Journal:  Nat Chem       Date:  2011-06-23       Impact factor: 24.427

  1 in total

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