Literature DB >> 12945030

Epidural clonidine relieves intractable neuropathic itch associated with herpes zoster-related pain.

Mohamed A Elkersh1, Thomas T Simopoulos, Atif B Malik, Eleanor H Cho, Zahid H Bajwa.   

Abstract

OBJECTIVE: We present a case of intense herpes zoster-related pain and itching in the ophthalmic division of the trigeminal nerve (V1). Successful pain and itch management was achieved after insertion of a high thoracic epidural catheter with a continuous infusion of bupivacaine and clonidine. CASE REPORT: A 73-year-old woman with metastatic malignant melanoma developed acute herpes zoster-related pain and itching unresponsive to conventional oral medications. The patient described severe and frequent attacks of lancinating pain occurring in the dermatomal distribution of the left ophthalmic division of the trigeminal nerve. She also had a disturbing itch in the same distribution as her pain. The patient had significant reduction in the frequency and intensity of the lancinating attacks after placement of a thoracic epidural catheter with continuous infusion of 1 microg/mL clonidine and 0.05% bupivacaine. The itching resolved completely as well.
CONCLUSION: High thoracic epidural infusion of bupivacaine and clonidine was beneficial in relieving neuropathic itch in a patient with acute herpes zoster-related pain in the distribution of the trigeminal nerve.

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Year:  2003        PMID: 12945030     DOI: 10.1016/s1098-7339(03)00182-2

Source DB:  PubMed          Journal:  Reg Anesth Pain Med        ISSN: 1098-7339            Impact factor:   6.288


  8 in total

Review 1.  [Interactions between itch and pain].

Authors:  M Schmelz
Journal:  Hautarzt       Date:  2006-05       Impact factor: 0.751

2.  Pulsed radiofrequency to the great occipital nerve for the treatment of intractable postherpetic itch: a case report.

Authors:  De-Fang Ding; Rong-Chun Li; Qiu-Ju Xiong; Ling Zhou; Hong-Bing Xiang
Journal:  Int J Clin Exp Med       Date:  2014-10-15

Review 3.  Neuropathic itch.

Authors:  Anne Louise Oaklander
Journal:  Semin Cutan Med Surg       Date:  2011-06

4.  Investigation of the Correlation between Postherpetic Itch and Neuropathic Pain over Time.

Authors:  Rie Ishikawa; Masako Iseki; Rie Koga; Eiichi Inada
Journal:  Pain Res Manag       Date:  2018-12-02       Impact factor: 3.037

Review 5.  [Neuropathic pruritus-Evidence-based treatment recommendations].

Authors:  Panoraia Baka; Frank Birklein
Journal:  Nervenarzt       Date:  2022-08-11       Impact factor: 1.297

6.  Analgesic effect of dexmedetomidine in a patient with herpetic stomatitis after living-donor lung transplantation.

Authors:  Yoshifumi Ohashi; Noriyuki Ohta; Osamu Hirao; Akinori Uchiyama; Takashi Mashimo; Yuji Fujino
Journal:  J Anesth       Date:  2008-08-07       Impact factor: 2.078

Review 7.  Common and discrete mechanisms underlying chronic pain and itch: peripheral and central sensitization.

Authors:  Chengjin Li; Hee Jin Kim; Seung Keun Back; Heung Sik Na
Journal:  Pflugers Arch       Date:  2021-07-10       Impact factor: 3.657

8.  Effect of 2% lidocaine continuous epidural infusion for thoracic or lumbar herpes-zoster-related pain.

Authors:  Shao-Jun Li; Dan Feng
Journal:  Medicine (Baltimore)       Date:  2018-08       Impact factor: 1.889

  8 in total

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