Literature DB >> 12943850

Combined metal catalysis and biocatalysis for an efficient deracemization process.

Oscar Pàmies1, Jan E Bäckvall.   

Abstract

Driven by the demand to enhance the economic balance of chemical processes, the transformation of a racemate into a single stereoisomer (the deracemization process) is one of the most important areas of research. The recent development of the combined use of enzyme and metal catalysis has led to efficient deracemization processes. Dynamic kinetic resolution and cyclic deracemization processes have shown particular promise in this area.

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Year:  2003        PMID: 12943850     DOI: 10.1016/s0958-1669(03)00097-1

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  4 in total

1.  Enantioselective alpha-hydroxylation of 2-arylacetic acid derivatives and buspirone catalyzed by engineered cytochrome P450 BM-3.

Authors:  Marco Landwehr; Lisa Hochrein; Christopher R Otey; Alex Kasrayan; Jan-E Bäckvall; Frances H Arnold
Journal:  J Am Chem Soc       Date:  2006-05-10       Impact factor: 15.419

2.  One-pot synthesis of enantiopure syn-1,3-diacetates from racemic syn/anti mixtures of 1,3-diols by dynamic kinetic asymmetric transformation.

Authors:  Michaela Edin; Johannes Steinreiber; Jan-E Bäckvall
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-06       Impact factor: 11.205

3.  Synthesis of Enantiopure Sulfoxides by Concurrent Photocatalytic Oxidation and Biocatalytic Reduction.

Authors:  Sarah Bierbaumer; Luca Schmermund; Alexander List; Christoph K Winkler; Silvia M Glueck; Wolfgang Kroutil
Journal:  Angew Chem Int Ed Engl       Date:  2022-03-04       Impact factor: 16.823

4.  Microbial Hydrolysis of Racemic β-Aryl-γ-ethylidene-γ-lactones and Antifeedant Activity of the Products against Alphitobius diaperinus Panzer.

Authors:  Andrzej Skrobiszewski; Witold Gładkowski; Marcelina Mazur; Maryla Szczepanik; Gabriela Maciejewska; Czesław Wawrzeńczyk
Journal:  Molecules       Date:  2018-06-23       Impact factor: 4.411

  4 in total

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