| Literature DB >> 12943789 |
Irama Ramírez1, Alfredo Carabot, Pablo Meléndez, Juan Carmona, Manuel Jimenez, Asmita V Patel, Trevor A Crabb, Gerald Blunden, Peter D Cary, Simon L Croft, Manuel Costa.
Abstract
From the aerial parts of Cissampelos pareira L. (Menispermaceae), a chalcone-flavone dimer has been isolated which, mainly from NMR spectroscopic and MS data, was proved to be 2-(4-hydroxy-3-methoxyphenyl)-7-(4-methoxyphenyl)-6-(2-hydroxy-4,6-dimethoxybenzoyl)-furano[3,2-g]benzopyran-4-one. This has been assigned the trivial name cissampeloflavone. The compound has good activity against Trypanosoma cruzi and T. brucei rhodesiense and has a low toxicity to the human KB cell line.Entities:
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Year: 2003 PMID： 12943789 DOI： 10.1016/s0031-9422(03)00241-3
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072