| Literature DB >> 12943777 |
Zimin Liu1, Paul R Jensen, William Fenical.
Abstract
Two metabolites, phomoxin and phomoxide, as well as the previously synthesized antibiotic eupenoxide, have been isolated from the fermentation broth of a marine-derived fungus of the genus Phoma (strain CNC-651). The new compounds are highly oxygenated polyketides of a new structural class. Phomoxin contains an unusual cyclic carbonate functionality that is rare among natural products. The structures of the new metabolites were assigned by spectroscopic methods that relied heavily on 2D NMR spectroscopic analysis.Entities:
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Year: 2003 PMID: 12943777 DOI: 10.1016/s0031-9422(03)00272-3
Source DB: PubMed Journal: Phytochemistry ISSN: 0031-9422 Impact factor: 4.072